{"id":1018,"date":"2022-03-08T12:07:10","date_gmt":"2022-03-08T12:07:10","guid":{"rendered":"https:\/\/blogs.ncl.ac.uk\/bns\/?p=1018"},"modified":"2022-03-21T20:43:38","modified_gmt":"2022-03-21T20:43:38","slug":"the-legacy-of-henrietta-lacks","status":"publish","type":"post","link":"https:\/\/blogs.ncl.ac.uk\/bns\/the-legacy-of-henrietta-lacks\/","title":{"rendered":"The Legacy of Henrietta Lacks"},"content":{"rendered":"\n<hr class=\"wp-block-separator\" \/>\n\n\n\n<p>By Evangelia Rakou Stage 2 Biomedical Sciences Student<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span style=\"text-decoration: underline\">Who is Henrietta Lacks?<\/span><\/h2>\n\n\n\n<p class=\"has-text-align-left\">It might come as a surprise to you that one of the people who changed the course of medical research was not even a scientist herself. <a rel=\"noreferrer noopener\" href=\"https:\/\/en.wikipedia.org\/wiki\/Henrietta_Lacks\" target=\"_blank\">Henrietta Lacks<\/a> was an\u202fAfrican American\u202fwoman and mother of five who died from cervical cancer in 1951. <\/p>\n\n\n\n<p class=\"has-text-align-left\">After complaining of vaginal bleeding, she was diagnosed with the disease and sadly\u202fpassed\u202faway several months after her\u202fdiagnosis. However, her cells continue to\u202fimpact\u202fthe world and revolutionise modern medicine years after her death.<\/p>\n\n\n\n<!--more-->\n\n\n\n<hr class=\"wp-block-separator\" \/>\n\n\n\n<h2 class=\"wp-block-heading\"><span style=\"text-decoration: underline\"><strong>HeLa cells<\/strong>&nbsp;<\/span><\/h2>\n\n\n\n<p>Henrietta\u2019s cells were removed during biopsy and were cultured for clinical evaluation. It was\u202fobserved\u202fthat the cells were doubling after 20-24 hours unlike\u202fprevious\u202fspecimens that died out.&nbsp;<\/p>\n\n\n\n<div class=\"wp-block-image\"><figure class=\"aligncenter size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/blogs.ncl.ac.uk\/bns\/files\/2022\/01\/HeLa-cells.png\" alt=\"\" class=\"wp-image-1019\" width=\"415\" height=\"257\" srcset=\"https:\/\/blogs.ncl.ac.uk\/bns\/files\/2022\/01\/HeLa-cells.png 352w, https:\/\/blogs.ncl.ac.uk\/bns\/files\/2022\/01\/HeLa-cells-300x186.png 300w\" sizes=\"auto, (max-width: 415px) 100vw, 415px\" \/><figcaption><em>Depiction of HeLa cells. Photo by HeitiPaves on Unsplash<\/em><\/figcaption><\/figure><\/div>\n\n\n\n<p>The cells were propagated shortly before Henrietta\u2019s death without her&nbsp;consent,&nbsp;they then became the source of the <a href=\"https:\/\/www.thermofisher.com\/uk\/en\/home\/technical-resources\/cell-lines\/h\/cell-lines-detail-35.html?ef_id=CjwKCAiAtdGNBhAmEiwAWxGcUnGIMOEjv5APqQHP95zrLAaQDXYk5cAalBcnceKcqgVuvpeStE52DxoCPHIQAvD_BwE:G:s&amp;s_kwcid=AL!3652!3!541399016552!!!g!!&amp;cid=bid_clb_cce_r01_co_cp0000_pjt0000_bid00000_0se_gaw_dy_pur_con&amp;s_kwcid=AL!3652!3!541399016552!!!g!!&amp;gclid=CjwKCAiAtdGNBhAmEiwAWxGcUnGIMOEjv5APqQHP95zrLAaQDXYk5cAalBcnceKcqgVuvpeStE52DxoCPHIQAvD_BwE\">HeLa cell line<\/a>, the first immortalized human cell line to reproduce infinitely in the lab and are now commonly used around the world. The culture was named after the first two&nbsp;letters&nbsp;of her first and last&nbsp;name,&nbsp;but the real name was not revealed until after a public leak in the 1970s.<\/p>\n\n\n\n<div class=\"wp-block-image\"><figure class=\"aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"408\" height=\"247\" src=\"https:\/\/blogs.ncl.ac.uk\/bns\/files\/2022\/01\/Empire-State-Building.png\" alt=\"\" class=\"wp-image-1020\" srcset=\"https:\/\/blogs.ncl.ac.uk\/bns\/files\/2022\/01\/Empire-State-Building.png 408w, https:\/\/blogs.ncl.ac.uk\/bns\/files\/2022\/01\/Empire-State-Building-300x182.png 300w\" sizes=\"auto, (max-width: 408px) 100vw, 408px\" \/><figcaption><em>Did you know that if all the HeLa cells were put together, it would outweigh 100 Empire State Buildings? Photo by Shooter_Sam on Unsplash<\/em><\/figcaption><\/figure><\/div>\n\n\n\n<p>By 2009, more than 60,000&nbsp;scientific articles had been published about research done on HeLa cells and that number increases steadily at a rate of more than 300&nbsp;papers each month. Due to the uniqueness of the HeLa cells they&nbsp;have been used as artwork in museums.<\/p>\n\n\n\n<hr class=\"wp-block-separator\" \/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong><span style=\"text-decoration: underline\">Revolutionizing medicine<\/span><\/strong><\/h2>\n\n\n\n<p>HeLa cells have contributed to a handful of medical breakthroughs over the past several decades. From the development of the polio vaccine leading to polio eradication, to studying the effects of zero gravity in outer space and to the study of leukemia, the AIDS virus and cancer, HeLa cells have changed medicine.<\/p>\n\n\n\n<p>Although other cells lines are used today such as Chinese hamster ovary cells or insect epithelial cells, HeLa has supported&nbsp;numerous&nbsp;medical advances and&nbsp;remains&nbsp;the&nbsp;most used&nbsp;cell line.<\/p>\n\n\n\n<hr class=\"wp-block-separator\" \/>\n\n\n\n<h2 class=\"wp-block-heading\"><span style=\"text-decoration: underline\">Ethics<\/span><\/h2>\n\n\n\n<p>Henrietta Lacks has also changed the course of&nbsp;medical&nbsp;research in a bidirectional way. Except&nbsp;for&nbsp;the many medical research applications, Henrietta\u2019s story led to the rewriting of the rules around ethics in healthcare. Eventually, stronger rules governing the use of specimens, medical records privacy, and communication with tissue donors and participants were&nbsp;established&nbsp;and informed consent became the cornerstone of ethical medical research.<\/p>\n\n\n\n<div class=\"wp-block-image\"><figure class=\"aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"350\" height=\"412\" src=\"https:\/\/blogs.ncl.ac.uk\/bns\/files\/2022\/01\/Hippocrates-1.png\" alt=\"\" class=\"wp-image-1022\" srcset=\"https:\/\/blogs.ncl.ac.uk\/bns\/files\/2022\/01\/Hippocrates-1.png 350w, https:\/\/blogs.ncl.ac.uk\/bns\/files\/2022\/01\/Hippocrates-1-255x300.png 255w\" sizes=\"auto, (max-width: 350px) 100vw, 350px\" \/><figcaption><em>Until the 1970&#8217;s, the only ethical commitment of medical investigators was the Hippocratic Oath, which was to &#8216;do no harm&#8217; to their patient. Photo by PhilSigin on Unsplash<\/em><\/figcaption><\/figure><\/div>\n\n\n\n<hr class=\"wp-block-separator\" \/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong><span style=\"text-decoration: underline\">New York Times Bestseller<\/span><\/strong><\/h2>\n\n\n\n<p>Author Rebecca Skloot&nbsp;wrote&nbsp;a book based on the true story of Henrietta Lacks, \u2018<a href=\"https:\/\/www.amazon.co.uk\/Immortal-Life-Henrietta-Lacks\/dp\/0330533444\/ref=asc_df_0330533444\/?tag=googshopuk-21&amp;linkCode=df0&amp;hvadid=311043780415&amp;hvpos=&amp;hvnetw=g&amp;hvrand=6058673744555011812&amp;hvpone=&amp;hvptwo=&amp;hvqmt=&amp;hvdev=c&amp;hvdvcmdl=&amp;hvlocint=&amp;hvlocphy=9046781&amp;hvtargid=pla-453292765171&amp;psc=1&amp;th=1&amp;psc=1\">The Immortal Cells of Henrietta Lacks\u2019<\/a>. The book introduces Henrietta Lacks and narrates a riveting story of the collision between ethics, race, and medicine. It is a complex story connected to the dark history of experimentation on African Americans and the birth of bioethics.<\/p>\n\n\n\n<div class=\"wp-block-image\"><figure class=\"aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"295\" height=\"356\" src=\"https:\/\/blogs.ncl.ac.uk\/bns\/files\/2022\/01\/Book.png\" alt=\"\" class=\"wp-image-1023\" srcset=\"https:\/\/blogs.ncl.ac.uk\/bns\/files\/2022\/01\/Book.png 295w, https:\/\/blogs.ncl.ac.uk\/bns\/files\/2022\/01\/Book-249x300.png 249w\" sizes=\"auto, (max-width: 295px) 100vw, 295px\" \/><figcaption><em>First page of &#8216;The Immortal Life of Henrietta Lacks&#8217; book<\/em><\/figcaption><\/figure><\/div>\n\n\n\n<hr class=\"wp-block-separator\" \/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong><span style=\"text-decoration: underline\">Appreciation statue<\/span><\/strong><\/h2>\n\n\n\n<p>In early October 2021 and the 70th anniversary of Henrietta Lacks\u2019 death, a life-size bronze statue of her was unveiled in the heart of the <a href=\"https:\/\/www.bbc.co.uk\/news\/uk-england-bristol-58761785\">University of Bristol<\/a> campus to&nbsp;honour&nbsp;her \u2018immortal life\u2019. This statue marked the milestone of the first public sculpture of a black woman made by a black woman (artist Helen Wilson-Roe) in the UK.<\/p>\n\n\n\n<hr class=\"wp-block-separator\" \/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong><span style=\"text-decoration: underline\">Black History Month<\/span><\/strong><\/h2>\n\n\n\n<p>Black History Month serves as an outstanding way of remembering important people and events in the history of the African Diaspora.<\/p>\n\n\n\n<div class=\"wp-block-image\"><figure class=\"aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"306\" height=\"377\" src=\"https:\/\/blogs.ncl.ac.uk\/bns\/files\/2022\/03\/Martin-Luther-King.png\" alt=\"\" class=\"wp-image-1448\" srcset=\"https:\/\/blogs.ncl.ac.uk\/bns\/files\/2022\/03\/Martin-Luther-King.png 306w, https:\/\/blogs.ncl.ac.uk\/bns\/files\/2022\/03\/Martin-Luther-King-244x300.png 244w\" sizes=\"auto, (max-width: 306px) 100vw, 306px\" \/><figcaption>Dr Martin Luther King<\/figcaption><\/figure><\/div>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\"><p><em>&#8220;I look to a day when people will not be judged by the colour of their skin, but by the content of their character&#8221;<\/em><\/p><p><\/p><cite>Martin Luther King<\/cite><\/blockquote>\n\n\n\n<div style=\"height:1px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<hr class=\"wp-block-separator\" \/>\n\n\n\n<p>Henrietta Lacks is commonly referred to the mother of modern medicine due to her unimaginable contribution. She constitutes one of the&nbsp;numerous&nbsp;paradigms that reminds&nbsp;us of&nbsp;the appreciation and acknowledgement of Blackness and how it permeates science and other aspects of society.<\/p>\n\n\n\n<hr class=\"wp-block-separator\" \/>\n\n\n\n<p>Interested in studying&nbsp;<a href=\"https:\/\/www.ncl.ac.uk\/undergraduate\/degrees\/b100\/\">Biomedical Sciences<\/a>&nbsp;at Newcastle University?<\/p>\n\n\n\n<p>Take a look at our other posts on&nbsp;<a href=\"https:\/\/blogs.ncl.ac.uk\/bns\/category\/women-in-stem\/\">Women in STEM<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>By Evangelia Rakou Stage 2 Biomedical Sciences Student Who is Henrietta Lacks? It might come as a surprise to you that one of the people who changed the course of medical research was not even a scientist herself. Henrietta Lacks was an\u202fAfrican American\u202fwoman and mother of five who died from cervical cancer in 1951. After &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/blogs.ncl.ac.uk\/bns\/the-legacy-of-henrietta-lacks\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;The Legacy of Henrietta Lacks&#8221;<\/span><\/a><\/p>\n","protected":false},"author":4267,"featured_media":1035,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[168,162,155],"tags":[122,151,75,73,71],"class_list":["post-1018","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-all-posts","category-blog-series","category-women-in-stem","tag-biomedical-science","tag-black-history-month","tag-international-womens-day","tag-student-voice","tag-women-in-science"],"_links":{"self":[{"href":"https:\/\/blogs.ncl.ac.uk\/bns\/wp-json\/wp\/v2\/posts\/1018","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.ncl.ac.uk\/bns\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.ncl.ac.uk\/bns\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.ncl.ac.uk\/bns\/wp-json\/wp\/v2\/users\/4267"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.ncl.ac.uk\/bns\/wp-json\/wp\/v2\/comments?post=1018"}],"version-history":[{"count":16,"href":"https:\/\/blogs.ncl.ac.uk\/bns\/wp-json\/wp\/v2\/posts\/1018\/revisions"}],"predecessor-version":[{"id":1452,"href":"https:\/\/blogs.ncl.ac.uk\/bns\/wp-json\/wp\/v2\/posts\/1018\/revisions\/1452"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/blogs.ncl.ac.uk\/bns\/wp-json\/wp\/v2\/media\/1035"}],"wp:attachment":[{"href":"https:\/\/blogs.ncl.ac.uk\/bns\/wp-json\/wp\/v2\/media?parent=1018"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.ncl.ac.uk\/bns\/wp-json\/wp\/v2\/categories?post=1018"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.ncl.ac.uk\/bns\/wp-json\/wp\/v2\/tags?post=1018"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}