MRC / NIHR: Multimorbidity in the UK population: understanding disease clustering

https://mrc.ukri.org/funding/browse/multimorbidity/multimorbidity-in-the-uk-population-understanding-disease-clustering/

Opens: 30/07/18

Deadline: 09/10/18

Amount: £600k (£3m total budget)

Duration: 36 months

The Medical Research Council (MRC) and the National Institute for Health Research (NIHR) are issuing a joint call for research projects into disease clustering in multimorbidity.

Funding is being made available for exploratory or hypothesis-driven research that will systematically identify or explore common disease clusters, their distributions in diverse groups, multimorbidity trajectories and/or underpinning mechanisms across the life course.

The call aims to support integrative population and patient studies using existing infrastructure and data sources including established cohorts, surveys, biobanks, and primary and secondary care data to identify new clusters of multimorbidity, biological, environmental, behavioural and socioeconomic multimorbidity risk factors, biomarkers and disease associations underpinned by common mechanistic pathways or induced by a pre-existing condition or its treatment.

Applications are considered that will contribute to building the evidence base for more focused research on specific types of multimorbidity or will generate data to enable larger-scale experimental medicine and stratified medicine studies.

Awards are expected to help establish new and galvanise existing research collaborations between clinical and academic experts from different research fields.

The scope of the call includes but is not limited to the following research topics:

  • Disease clustering in defined population/patient groups.
  • Addressing prevalence and changes in multimorbidity during the life course (e.g. in childhood, during pregnancy or postpartum period).
  • Social patterning and health inequalities associated with multimorbidity.
  • Shared mechanistic pathways in common co-morbidities.
  • Multimorbidity biomarkers, early predictors and genetic associations.
  • Innovative methodological approaches, tools and technologies for capturing and measuring patients’ complexities in the context of multimorbidity.
  • Enriching data for established population and clinical cohorts.

Proposals can only be led by an eligible UK-based Principal Investigator.

Overseas Co-investigators are permitted as long as the focus of a proposal is on the UK population.

NU Innovates: Collaborate with GSK, Monday July 30th, 11-12, Dental Lecture Theatre E

Dear colleagues

I am writing to you as you have previously attended or expressed an interest in our NU Innovates Seminar Series, http://www.newcastleptd.com/nu-innovates/ .  I would also like to remind you that the Newcastle MRC Proximity to Discovery Reactive scheme is always open, http://www.newcastleptd.com/apply/ !

The fifth NU Innovates Seminar takes place next week, and offers an opportunity to learn about opportunities to collaborate with GSK.

NU Innovates: Collaborate with GSK

Guest Speaker: Iain Uings, Director of Discovery Partnerships with Academia at GlaxoSmithKline

Date/Time: Monday 30th July 2018, 11:00 – 12.00

Venue: Dental Lecture Theatre E, Medical School

Iain Uings, will provide details of the GSK Discovery Partnership for Academia scheme (http://www.dpac.gsk.com/).  This scheme is designed to provide industrial drug discovery resources and expertise to academic researchers. GSK is interested in any disease area and based on any treatment modality, be it small molecule or biopharmaceutical. GSK will undertake projects starting from early screening to late lead optimisation.

A DPAc partnership offers you:

  • A single partner to develop an idea into a therapeutic
  • Collaboration with GSK researchers with the skills and resources to meet your needs
  • Access to state-of-the-art drug discovery platforms
  • A financial share in the success of any future medicines

To register for this event please email me,  Sarah.Greenhalgh@newcastle.ac.uk.

The NU Innovates program is supported by the University’s MRC Proximity to Discovery scheme.

Lister Institute Research Prizes C/D 12 October 2018

Dear All

I would be grateful if you could circulate this notice of the 2019 Lister Institute Research Prize

http://www.lister-institute.org.uk/launch-of-the-2019-lister-fellowship-applications/

Closing date: Friday 12 October 2018

£250,000 over 5 years

Candidates must have more than 3 and less than 10 years’ postdoctoral experience on 1 October 2019 and

must have guaranteed employment for the first three years of the notional five years of the award

Eligibility

  • Any tenured or non-tenured researcher (scientist or clinician) working in an eligible UK or Irish institution is allowed to apply; provided that their personal salary is secure, from another source, and guaranteed for a minimum of the first three years of the award.
  • The recipient does not need to be a UK national, but they must have a position in a UK or Republic of Ireland (ROI) institution for at least the first three years of the award.
  • There is no age restriction, but the individual must, at the time of taking up the award, have a minimum of 3 or a maximum of 10 years’ research experience (allowance will be made for career breaks).
  • The individual may concurrently hold awards, such as a fellowship, programme, or project grant(s), from other organisations, or be employed by them.
  • Applicants may be scientifically trained undertaking full-time research, medically qualified still undergoing some speciality training and/or leading a research project with more than 3 but less than 10 years post-doctoral experience (post PhD or MD, whichever is the earlier).
  • Prizes are ideal for researchers just starting their own independent research group, or for group leaders looking to research new areas not covered by current awards.
  • The Lister Institute seeks diversity in its Prize winners and their research areas. The Institute is delighted that over the years female researches have been well represented amongst its prize-winners, which have been in the same gender ratio as initial applications.
  • The Institute is aware that personal circumstances vary and that there are unavoidable factors that limit research time (e.g. maternity leave, family commitments). Please contact the Lister Institute directly if you would like to discuss your eligibility

Those thinking of making an application should contact Gwen Averley gwen.averley@ncl.ac.uk and/or Darren Airey darren.airey@ncl.ac.uk

With many thanks

Gwen

2019 Terms and Conditions.doc

2019 Notice

2018 Prizewinners

Northern and Yorkshire Annual Rheumatology Meeting 2018

Registration: This event is free. However we do need people to register for the event. This helps us in the planning of the event, plotting which rooms are best to use, organising the catering and making sure we comply with Health and Safety regulations. This link(via Eventbrite) will be active until 12th September 2018, which is the deadline for registration. If you wish to see if spaces are available to register after this date, or have any other questions about the form or any difficulty in using it please contact janet.herdman@ncl.ac.uk.

Abstract submission instructions: Abstracts should be limited to 1 side of A4 (12 point font) and may include 1 figure; they should be sent by e-mail to Janet Herdman (janet.herdman@ncl.ac.uk) no later than 17:00 on Monday 3rd September.

Clinical cases for the morning session, please contact Mike Green (mike.green@hdft.nhs.uk) asap
For further details see our website
Or follow us on Facebook (Northern and Yorkshire Rheumatology Meeting) or Twitter (@NYRCMeeting)

Starter Grants for Clinical Lecturers: Round 20 open for applications

Are you a research-active Clinical Lecturer looking to develop and strengthen your research? Round 20 now open for applications

We offer grants of up to £30,000 to cover the cost of research consumables, enabling research-active Clinical Lecturers to gather data to strengthen their bids for longer-term fellowships and funding.

To be eligible to apply you must:

  • Be a research-active Clinical Lecturer (or equivalent eligible post for Veterinary Clinicians)
  • Have a PhD or MD
  • Hold a medical, dental or veterinary undergraduate degree
  • Be within higher specialty training (except from GPs who may apply post-CCT)

We welcome applications from clinicians in human, dental and veterinary medicine. For more information on eligibility, please see the Academy’s Starter Grant webpage.

Deadline for applications: 10 September 2018

This scheme is run by the Academy of Medical Sciences with the support of the Wellcome Trust, Medical Research Council, British Heart Foundation, Arthritis Research UK, Diabetes UK and British Thoracic Society (through the Helen and Andrew Douglas bequest).

Alzheimer’s Research UK David Hague Early Career Investigator of the Year Award 2019

Applications Now Open for Alzheimer’s Research UK David Hague Early Career Investigator of the Year Award 2019

The David Hague Early Career Investigator of the Year Award aims to recognise the contribution of an outstanding early career researcher in the field of biomedical dementia research. Alzheimer’s Research UK (ARUK) also aims to raise the profile of excellence in dementia research through the award.

The award consists of £25,000 in research expenses and a personal prize of £1,500, as well as the winner’s expenses for attending ARUK’s Annual Research Conference which will be held in Harrogate, UK, 19-20 March 2019.

Candidates will be judged by an external panel of prominent researchers, who will look for excellence in scientific research and a significant contribution to the field of dementia research as demonstrated through the candidates’ defining research outputs and essay. Early career researchers from anywhere in the world with less than 10 years post-PhD experience (excluding career breaks) are eligible to apply. Entrants must submit a 1,000 word essay explaining how their three defining research outputs have contributed to their development across ARUK’s Early Career Research Framework.

The winner will be notified in December 2018, and will be required to present at the ARUK Annual Research Conference.

The closing date for entries is 28 September 2018 (12pm UTC+1).

The direct link to this scheme is: https://www.alzheimersresearchuk.org/for-researchers/research-opportunities/early-career-award/

There is also a very detailed 3 page summary here: https://www.alzheimersresearchuk.org/wp-content/uploads/2015/03/Draft-David-Hague-Early-Career-Investigator-Award-Description-2018-19.pdf

Industrial Strategy Challenge Fund (ISCF): Transforming Construction Network Plus

Expressions of interest by leaderships teams for a network plus as part of the Transforming Construction challenge has been announced under the ISCF.  Network plus are intended to create a new community linking together other investments made under the ISCF Transforming Construction Challenge with the broader research base, relevant business and wider stakeholders.  It will engage the network membership through events, communications and small scale funding call.

A single network plus will be funded for up to £2.5 million at 100% fEC – for further information please see the ESRC website.

If you are interested in this call please can you contact Fiona McCusker (fiona.mccusker@ncl.ac.uk), Business Development Manager, to discuss further as there has been discussion in developing a proposal.

ESRC: Innovation in Social Care Collaborative Grants

Innovation in Social Care Collaborative Grants

ESRC invite outline application for large collaborative grants on Innovation in Social Care.  Grants are expected to be between £1 million and £2 million (100% fEC), for a duration of up to 60 months and to be submitted by 16 October 2018.

Through this call, ESRC will fund social science-led research and knowledge exchange activity to understand how, why and where innovation happens in social care, to best understand how to improve people’s lives.  Each grant should be highly collaborative involving a range of disciplines and stakeholders through the research process, as well as including researchers with a strong track record.

Proposal should reflect the reality of how social care is experienced by care recipients and providers, their friends and families, and care professionals, as well as exploring the relationships between those involved.  All applicants should also consider the following, and clearly state how these will be addressed in their case for support:

  • Social care system
  • Theoretical and methodological approach
  • Impact of inequality
  • Place
  • Outcomes

Proposals are particularly welcomed that focus on one or more of the following (see page 3 of the call specification for further details):

  • Housing
  • Workforce
  • Relationships
  • Wider political and economic backdrop to social care

Timetable:

Closing date for outline proposals – 16 October 2018

Proposals shortlisted – December 2018

Closing date for full proposals – February 2019

Funding decisions – June 2019

Grants start – from 1 September 2019

Wellcome Trust International Fellowships – change to remit

Please could you circulate this information to researchers in your Institutes.It will be of interest to those working with Lower and Middle Income Countries.

The Wellcome Trust has recently revised their International Fellowship schemes. https://wellcome.ac.uk/news/update-public-health-and-tropical-medicine-fellowships

The Wellcome has amended the remit of the three schemes to now include everything within its remit (https://wellcome.ac.uk/funding/guidance/science-remit). They no longer just focus on Public Health and Tropical Medicine.

3 levels of fellowships are offered: International Master’s Fellowships, International Training Fellowships & International Intermediate Fellowships. They are open to clinicians and non-clinicians.

These schemes offer nationals of Lower and Middle Income Countries (LMICs) the chance to work in an LMIC and research a health priority in the setting.

This may be of interest to researchers who have LMIC partners or wish to develop LMIC relationships. Although the award could not be held at Newcastle University, a period of training / collaboration could be undertaken here.