{"id":85,"date":"2018-06-15T15:27:28","date_gmt":"2018-06-15T14:27:28","guid":{"rendered":"https:\/\/blogs.ncl.ac.uk\/kengng\/?page_id=85"},"modified":"2026-04-10T13:21:50","modified_gmt":"2026-04-10T12:21:50","slug":"publications","status":"publish","type":"page","link":"https:\/\/blogs.ncl.ac.uk\/kengng\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"\n<p>Please see <a href=\"https:\/\/scholar.google.com\/citations?hl=en&amp;user=ql53U9AAAAAJ&amp;view_op=list_works&amp;sortby=pubdate\" target=\"_blank\" rel=\"noreferrer noopener\">Google Scholar<\/a> for full list.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2026<\/h2>\n\n\n\n<p><a href=\"https:\/\/doi.org\/10.1016\/j.jconrel.2026.114894\" target=\"_blank\" rel=\"noreferrer noopener\">Transdermal delivery and formulation design of opioids: Where are we now and where are we heading?<\/a><br>Liang YM, Azizi J, Ng KW, Goh CF<br>Journal of Controlled Release. 2026:114894<\/p>\n\n\n\n<p><a href=\"https:\/\/doi.org\/10.1016\/j.ohx.2025.e00735\" target=\"_blank\" rel=\"noreferrer noopener\">Building Otto: An open-source Franz diffusion cell autosampler for automating in vitro skin permeation studies<\/a><br>Ng KW, Archbold L, Lau WM<br>HardwareX. 2026;25:e00735<\/p>\n\n\n\n<p><a href=\"https:\/\/doi.org\/10.1016\/B978-0-443-30184-1.00024-7\" target=\"_blank\" rel=\"noreferrer noopener\">Recent developments of micro\/nanoneedles for cosmetic delivery<\/a><br>Goh CF, Ramadon D, Ng KW, Punu GF, Lee JY<br>Nanotechnology in Cosmeceuticals. 2026:433-456<\/p>\n\n\n\n<p><a href=\"https:\/\/doi.org\/10.1016\/j.ijpharm.2025.126490\" target=\"_blank\" rel=\"noreferrer noopener\">Elastin-derived peptide hydrogels for sustained dermal delivery of tetrapeptide-21<\/a> <br>Stephenson H, Lim A, Dupuy R, Brun S, Armstrong A, Okunola N, Li NA, Hilkens CMU, Novakovic K, Hills S, Ng KW, Al Musaimi O<br>International Journal of Pharmaceutics. 2026;689:126490<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2025<\/h2>\n\n\n\n<p><a href=\"https:\/\/doi.org\/10.1016\/j.ijpharm.2025.125932\" target=\"_blank\" rel=\"noreferrer noopener\">Engineering and in vitro evaluation of semi-dissolving, hydrogel-forming polymeric microneedles for sustained-release drug delivery<\/a><br>Abdelghany TM, Vo N, Vukajlovic D, Smith E, Wong JZ, Jackson E, Hilkens CMU, Lau WM, Ng KW, Novakovic K<br>International Journal of Pharmaceutics. 2025; 682(15):125932<\/p>\n\n\n\n<p><a href=\"https:\/\/doi.org\/10.1016\/j.xphs.2025.103837\" target=\"_blank\" rel=\"noreferrer noopener\">Validating Otto: a Franz diffusion cell autosampler to automate in vitro permeation studies<\/a><br>Chan HKY, Archbold L, Lau WM, Ng KW<br>Journal of Pharmaceutical Sciences. 2025;114(7):103837<\/p>\n\n\n\n<p><a href=\"https:\/\/doi.org\/10.1007\/s13346-025-01888-8\" target=\"_blank\" rel=\"noreferrer noopener\">Assessing the integrity and mechanical properties of commercial microneedles: innovation or fad?<\/a><br>Lee JY, Dong SH, Ng KW, Goh CF<br>Drug Delivery and Translational Research. 2025;15:3986-4003<\/p>\n\n\n\n<p><a href=\"http:\/\/A multifunctional platform for the production and customization of polymer-based microneedle devices\" target=\"_blank\" rel=\"noreferrer noopener\">A multifunctional platform for the production and customization of polymer-based microneedle devices<\/a><br>Bocchino A, Marquez-Grana C, Singh OP, Melnik E, Kurzhals S, Mutinati GC, Coulman S, Martin C, Ng KW, Vergilio MM, Birchall J, Donovan P, Galvin P, O&#8217;Mahony C<br>Sensor and Actuators A: Physical. 2025;388:116491<\/p>\n\n\n\n<p><a href=\"https:\/\/doi.org\/10.17632\/cvc9vxjgn9\" target=\"_blank\" rel=\"noreferrer noopener\">Design files for Otto, the Franz diffusion cell autosampling robot<\/a><br>Ng KW<br>Mendeley Data, 2025<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2024<\/h2>\n\n\n\n<p><a href=\"https:\/\/doi.org\/10.3390\/gels10080531\" target=\"_blank\" rel=\"noreferrer noopener\">Elastin-derived peptide-based hydrogels as a potential drug delivery system<\/a><br>Al Musaimi O, Ng KW, Gavva V, Mercado-Valenzo OM, Haroon HB, Williams DR<br>Gels. 2024;10(8):531<\/p>\n\n\n\n<p><a href=\"https:\/\/doi.org\/10.1016\/j.ijbiomac.2024.133850\" target=\"_blank\" rel=\"noreferrer noopener\">Mathematical modelling of genipin-bovine serum albumin interaction using fluorescence intensity measurements<\/a><br>Vukajlovic D, Timmons R, Macesic S, Sanderson J, Xie F, Abdelghany TM, Smith E, Lau WM, Ng KW, Novakovic K<br>International Journal of Biolological Macromolecules. 2024;276(Pt 1):133850<\/p>\n\n\n\n<p><a href=\"https:\/\/doi.org\/10.1039\/D4PM00024B\" target=\"_blank\" rel=\"noreferrer noopener\">In vitro evaluation of microneedle strength: A comparison of test configurations and experimental insights<\/a><br>Alrimawe BH, Lee JY, Ng KW, Goh CF<br>RSC Pharmaceutics. 2024;1:227-233<\/p>\n\n\n\n<p><a href=\"https:\/\/doi.org\/10.1016\/j.ijpharm.2023.123706\" target=\"_blank\" rel=\"noreferrer noopener\">Vac-and-fill: A micromoulding technique for fabricating microneedle arrays with vacuum-activated, hands-free mould-filling<\/a><br>Smith E, Lau WM, Abdelghany TM, Vukajlovic D, Novakovic K, Ng KW<br>International Journal of Pharmaceutics. 2024;650:123706<\/p>\n\n\n\n<p><a href=\"https:\/\/doi.org\/10.46793\/Phys.Chem24I.139N\" target=\"_blank\" rel=\"noreferrer noopener\">Chitosan hydrogen based microneedle technology for prolonged release of actives<\/a><br>Novakovic K, Hutchinson E, Lau WM, Abdelghany T, Ng KW<br>Proceedings of the 17th International Conference on Fundamental and Applied Aspects of Physical Chemistry, Volume I. 2024:139-141<\/p>\n\n\n\n<!--more-->\n\n\n\n<h2 class=\"wp-block-heading\">2022<\/h2>\n\n\n\n<p><a href=\"https:\/\/doi.org\/10.5920\/bjpharm.1164\" target=\"_blank\" rel=\"noreferrer noopener\">A microneedle-microplate platform to detect biomarkers in the skin<\/a><br>Dixon RV, Lau WM, Ng KW<br>British Journal of Pharmacy. 2022;7(2):1164<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2021<\/h2>\n\n\n\n<p><a href=\"https:\/\/doi.org\/10.1016\/j.apsb.2021.02.010\" target=\"_blank\" rel=\"noreferrer noopener\">Microneedle-based devices for point-of-care infectious disease diagnostics<\/a><br>Dixon RV, Skaria E, Lau WM, Manning P, Birch-Machin MA, Moghimi SM, Ng KW<br>Acta Pharmaceutica Sinica B. 2021;11(8):2344-2361<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2020<\/h2>\n\n\n\n<p><a href=\"https:\/\/doi.org\/10.3390\/pharmaceutics12080751\" target=\"_blank\" rel=\"noreferrer noopener\">Silica nanoparticles in transmucosal drug delivery<\/a><br>M Ways TM, Ng KW, Lau WM, Khutoryanskiy VV<br>Pharmaceutics. 2020;12(8):751<\/p>\n\n\n\n<p><a href=\"https:\/\/doi.org\/10.33218\/001c.13658\" target=\"_blank\" rel=\"noreferrer noopener\">The diagnostic potential of microneedles in infectious diseases<\/a><br>Dixon RV, Lau WM, Moghimi SM, Ng KW<br>Precision Nanomedicine. 2020;3(4):629-640<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2019<\/h2>\n\n\n\n<p><a href=\"https:\/\/doi.org\/10.1016\/j.snb.2019.126652\" target=\"_blank\" rel=\"noreferrer noopener\">A novel versatile animal-free 3D tool for rapid low-cost assessment of immunodiagnostic microneedles<\/a><br>Totti S, Ng KW, Dale L, Lian G, Chen T, Velliou EG<br>Sensors and Actuators B: Chemical. 2019;296:126652<\/p>\n\n\n\n<p><a href=\"http:\/\/doi.org\/10.1021\/acs.analchem.8b04980\" target=\"_blank\" rel=\"noreferrer noopener\">Poly(lactic acid)\/carbon nanotube composite microneedle arrays for dermal biosensing<\/a><br>Skaria E, Patel BA, Flint MS, Ng KW<br>Analytical Chemistry. 2019;91(7):4436-4443<\/p>\n\n\n\n<p><a href=\"https:\/\/doi.org\/10.5920\/bjpharm.598\" target=\"_blank\" rel=\"noreferrer noopener\">The influence of oxygen and pressure on keratinocytes<\/a><br>Obeid KA, Williams AC, Ng KW, Lau WM<br>British Journal of Pharmacy. 2019;4(1):S6-S7<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2018<\/h2>\n\n\n\n<p><a href=\"https:\/\/doi.org\/10.33218\/prnano1(2).180709.1\" target=\"_blank\" rel=\"noreferrer noopener\">Skin biosensing and bioanalysis: what the future holds<\/a><br>Ng KW, Moghimi SM<br>Precision Nanomedicine. 2018;1(2):124-127<\/p>\n\n\n\n<p><a href=\"http:\/\/doi.org\/10.1016\/j.ejps.2018.06.032\" target=\"_blank\" rel=\"noreferrer noopener\">Synthesis of thiolated, PEGylated and POZylated silica nanoparticles and evaluation of their retention on rat intestinal mucosa in vitro<\/a><br>Ways TMM, Lau WM, Ng KW, Khutoryanskiy VV<br>European Journal of Pharmaceutical Sciences. 2018;122:230-238<\/p>\n\n\n\n<p><a href=\"https:\/\/blogs.ncl.ac.uk\/kengng\/files\/2019\/06\/totti2018-aiche-annual-meeting-pittsburgh.pdf\">A multifunctional versatile 3D melanoma model for rapid micro-needle based in situ detection of disease specific biomarkers<\/a><br>Totti S, Ng KW, Lian G, Chen T, Velliou EG<br>American Institute of Chemical Engineers Annual Meeting, Pittsburgh, PA, USA. 2018. ISBN: 978-0-8169-1108-0<\/p>\n\n\n\n<p><a href=\"https:\/\/doi.org\/10.3389\/fcimb.2018.00196\" target=\"_blank\" rel=\"noreferrer noopener\">Development of a high-throughput <em>ex-vivo<\/em> burn wound model using porcine skin, and its application to evaluate new approaches to control wound infection<\/a><br>Alves DR, Booth SP, Scavone P, Schellenberger P, Salvage J, Dedi C, Thet NT, Jenkins ATA, Waters R, Ng KW, Overall ADJ, Metcalfe AD, Nzakizwanayo J, Jones BV<br>Frontiers in Cellular Infection Microbiology. 2018;8:196<\/p>\n\n\n\n<p><a href=\"http:\/\/doi.org\/10.3390\/pharmaceutics10020051\" target=\"_blank\" rel=\"noreferrer noopener\">Penetration enhancement of topical formulations<\/a><br>Ng KW<br>Pharmaceutics. 2018;10(2):51<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2017<\/h2>\n\n\n\n<p><a href=\"https:\/\/doi.org\/10.1007\/978-3-662-53270-6_3\" target=\"_blank\" rel=\"noreferrer noopener\">Finite and infinite dosing<\/a><br>Lau WM, Ng KW<br>Percutaneous Penetration Enhancers &#8211; Drug Penetration Into\/Through the Skin. 2017:35-44<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2015<\/h2>\n\n\n\n<p><a href=\"https:\/\/doi.org\/10.1007\/s13346-015-0231-5\" target=\"_blank\" rel=\"noreferrer noopener\">Towards pain-free diagnosis of skin diseases through multiplexed microneedles: biomarker extraction and detection using a highly sensitive blotting method<\/a><br>Ng KW, Lau WM, Williams AC<br>Drug Delivery and Translational Research. 2015;5(4):387-96<\/p>\n\n\n\n<p><a href=\"https:\/\/doi.org\/10.1007\/978-3-662-47039-8_24\" target=\"_blank\" rel=\"noreferrer noopener\">Synergy between chemical penetration enhancers<\/a><br>Ng KW, Lau WM, Williams AC<br>Percutaneous Penetration Enhancers &#8211; Chemical Methods in Penetration Enhancement: Modification of the Stratum Corneum. 2015:373-385<\/p>\n\n\n\n<p><a href=\"https:\/\/doi.org\/10.1007\/978-3-662-45013-0_1\" target=\"_blank\" rel=\"noreferrer noopener\">Skin deep: the basics of human skin structure and drug penetration<\/a><br>Ng KW, Lau WM<br>In: Percutaneous Penetration Enhancers &#8211; Chemical Methods in Penetration Enhancement: Drug Manipulation Strategies and Vehicle Effects. 2015:3-11<\/p>\n\n\n\n<p><a href=\"https:\/\/doi.org\/10.1097\/CCM.0000000000000982\" target=\"_blank\" rel=\"noreferrer noopener\">Metabolic profiling of children undergoing surgery for congenital heart disease<\/a><br>Correia GD, Wooi Ng K, Wijeyesekera A, Gala-Peralta S, Williams R, MacCarthy-Morrogh S, Jim\u00e9nez B, Inwald D, Macrae D, Frost G, Holmes E, Pathan N. <br>Critical Care Medicine. 2015;43(7):1467-76<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2012<\/h2>\n\n\n\n<p><a href=\"https:\/\/doi.org\/10.1016\/j.ijpharm.2012.04.079\" target=\"_blank\" rel=\"noreferrer noopener\">Distribution of esterase activity in porcine ear skin, and the effects of freezing and heat separation<\/a> <br>Lau WM, Ng KW, Sakenyte K, Heard CM<br>International Journal of Pharmaceutics. 2012;433(1-2):10-5<\/p>\n\n\n\n<p><a href=\"http:\/\/doi.org\/10.1161\/CIRCULATIONAHA.111.063784\" target=\"_blank\" rel=\"noreferrer noopener\">Cardioprotective effects of insulin: how intensive insulin therapy may benefit cardiac surgery patients<\/a><br>Ng KW, Allen ML, Desai A, Macrae D, Pathan N<br>Circulation. 2012;125(5):721-8<\/p>\n\n\n\n<p><a href=\"https:\/\/doi.org\/10.1164\/rccm.201104-0715OC\" target=\"_blank\" rel=\"noreferrer noopener\">Intestinal injury and endotoxemia in children undergoing surgery for congenital heart disease<\/a><br>Pathan N, Burmester M, Adamovic T, Berk M, Ng KW, Betts H, Macrae D, Waddell S, Paul-Clark M, Nuamah R, Mein C, Levin M, Montana G, Mitchell JA<br>American  Journal of Respiratory and Critical Care Medicine. 2011;184(11):1261-9<\/p>\n\n\n\n<p><a href=\"https:\/\/doi.org\/10.1021\/mp200327k\" target=\"_blank\" rel=\"noreferrer noopener\">Therapeutic and cytotoxic effects of the novel antipsoriasis codrug, naproxyl-dithranol, on HaCaT cells<\/a><br>Lau WM, Ng KW, White AW, Heard CM<br>Molecular Pharmaceutics. 2011;8(6):2398-407<\/p>\n\n\n\n<p><a href=\"https:\/\/doi.org\/10.1097\/01.ccm.0000408627.24229.88\" target=\"_blank\" rel=\"noreferrer noopener\">Immune dysregulation in children undergoing surgery for congenital heart disease is marked by altered antigen sensing capability<\/a><br>Ng KW, Greco M, Allen M, Desai A, Macrae D, Bacon S, Gevers E, Inwald D, Pathan N<br>Critical Care Medicine. 2011;39:36<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2010<\/h2>\n\n\n\n<p><a href=\"https:\/\/doi.org\/10.1211\/jpp.62.06.0016\" target=\"_blank\" rel=\"noreferrer noopener\">Biodegradable microneedles for intra-epidermal vaccination<\/a><br>Ng KW, Pearton M, Allender CJ, Morrissey A, McLoughlin P, Birchall JC<br>Journal of Pharmacy and Pharmacology. 2010;62(6):798<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2009<\/h2>\n\n\n\n<p><a href=\"https:\/\/doi.org\/10.1016\/j.vaccine.2009.07.088\" target=\"_blank\" rel=\"noreferrer noopener\">Development of an ex vivo human skin model for intradermal vaccination: tissue viability and Langerhans cell behaviour<\/a><br>Ng KW, Pearton M, Coulman S, Anstey A, Gateley C, Morrissey A, Allender C, Birchall <br>Vaccine. 2009;27(43):5948-55<\/p>\n\n\n\n<p><a href=\"https:\/\/doi.org\/10.1211\/002235709789037044\" data-type=\"link\" data-id=\"https:\/\/doi.org\/10.1211\/002235709789037044\" target=\"_blank\" rel=\"noreferrer noopener\">Tissue viability and Langerhans cell behaviour in an ex-vivo human skin model for cutaneous DNA vaccination<\/a><br>Ng KW, Pearton M, Coulman S, Anstey A, Gateley C, Morrissey A, O&#8217;Mahony C, Allender C, Birchall J<br>Journal of Pharmacy and Pharmacology. 2009;61:A2-A3.<\/p>\n\n\n\n<p><a href=\"http:\/\/orca.cf.ac.uk\/6663\" target=\"_blank\" rel=\"noreferrer noopener\">Ex vivo immunological studies using excised human skin<\/a><br>Ng KW, Pearton M, Coulman S, Anstey AV, Gateley C, Morrissey A, Allender CJ, Birchall JC<br>British Journal of Dermatology. 2009;160(4):921<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2003<\/h2>\n\n\n\n<p><a href=\"https:\/\/doi.org\/10.1080\/10611860400003858\" target=\"_blank\" rel=\"noreferrer noopener\">Sustained polymeric delivery of gene silencing antisense ODNs, siRNA, DNAzymes and ribozymes: in vitro and in vivo studies<\/a><br>Khan A, Benboubetra M, Sayyed PZ, Ng KW, Fox S, Beck G, Benter IF, Akhtar S<br>Journal of Drug Targeting. 2004;12(6):393-404<br>Erratum in: Journal of Drug Targeting. 2004;12(7):473<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Please see Google Scholar for full list. 2026 Transdermal delivery and formulation design of opioids: Where are we now and where are we heading?Liang YM, Azizi J, Ng KW, Goh CFJournal of Controlled Release. 2026:114894 Building Otto: An open-source Franz diffusion cell autosampler for automating in vitro skin permeation studiesNg KW, Archbold L, Lau WMHardwareX. &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/blogs.ncl.ac.uk\/kengng\/publications\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Publications&#8221;<\/span><\/a><\/p>\n","protected":false},"author":3965,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-85","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/blogs.ncl.ac.uk\/kengng\/wp-json\/wp\/v2\/pages\/85","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.ncl.ac.uk\/kengng\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/blogs.ncl.ac.uk\/kengng\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.ncl.ac.uk\/kengng\/wp-json\/wp\/v2\/users\/3965"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.ncl.ac.uk\/kengng\/wp-json\/wp\/v2\/comments?post=85"}],"version-history":[{"count":318,"href":"https:\/\/blogs.ncl.ac.uk\/kengng\/wp-json\/wp\/v2\/pages\/85\/revisions"}],"predecessor-version":[{"id":1535,"href":"https:\/\/blogs.ncl.ac.uk\/kengng\/wp-json\/wp\/v2\/pages\/85\/revisions\/1535"}],"wp:attachment":[{"href":"https:\/\/blogs.ncl.ac.uk\/kengng\/wp-json\/wp\/v2\/media?parent=85"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}