{"id":1339,"date":"2025-06-01T12:12:52","date_gmt":"2025-06-01T11:12:52","guid":{"rendered":"https:\/\/blogs.ncl.ac.uk\/kengng\/?p=1339"},"modified":"2025-06-01T12:19:35","modified_gmt":"2025-06-01T11:19:35","slug":"assessing-the-integrity-and-mechanical-properties-of-commercial-microneedles-innovation-or-fad","status":"publish","type":"post","link":"https:\/\/blogs.ncl.ac.uk\/kengng\/news\/assessing-the-integrity-and-mechanical-properties-of-commercial-microneedles-innovation-or-fad\/","title":{"rendered":"Assessing the integrity and mechanical properties of commercial microneedles: innovation or fad?"},"content":{"rendered":"\n<hr class=\"wp-block-separator has-alpha-channel-opacity is-style-wide\" \/>\n\n\n\n<p><strong>Citation:<\/strong> Lee JY, Dong SH, Ng KW, Goh CF. <a href=\"https:\/\/blogs.ncl.ac.uk\/kengng\/publications\/\" data-type=\"page\" data-id=\"85\" target=\"_blank\" rel=\"noreferrer noopener\">Assessing the integrity and mechanical properties of commercial microneedles: innovation or fad?<\/a> Drug Deliv Transl Res. 2025. doi: 10.1007\/s13346-025-01888-8<\/p>\n\n\n\n<div class=\"wp-block-buttons is-content-justification-center is-layout-flex wp-container-core-buttons-is-layout-1 wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/doi.org\/10.1007\/s13346-025-01888-8\" target=\"_blank\" rel=\"noreferrer noopener\">Read Full-Text Article<\/a><\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity is-style-wide\" \/>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" src=\"https:\/\/media.springernature.com\/lw685\/springer-static\/image\/art%3A10.1007%2Fs13346-025-01888-8\/MediaObjects\/13346_2025_1888_Figa_HTML.png?as=webp\" alt=\"\" \/><\/figure>\n\n\n\n<p>In this collaborative paper\u2014our second with the Malaysian team led by <a href=\"https:\/\/www.linkedin.com\/in\/choonfugoh?miniProfileUrn=urn%3Ali%3Afsd_profile%3AACoAAAznpb0BGla_oHvrlO6triq_IyW3SUQDu0g&amp;lipi=urn%3Ali%3Apage%3Ad_flagship3_detail_base%3Bjc059UmqREez4GvjF3Pt3g%3D%3D\" data-type=\"link\" data-id=\"https:\/\/www.linkedin.com\/in\/choonfugoh?miniProfileUrn=urn%3Ali%3Afsd_profile%3AACoAAAznpb0BGla_oHvrlO6triq_IyW3SUQDu0g&amp;lipi=urn%3Ali%3Apage%3Ad_flagship3_detail_base%3Bjc059UmqREez4GvjF3Pt3g%3D%3D\" target=\"_blank\" rel=\"noreferrer noopener\">Dr Choon Fu Goh<\/a>\u2014we examine some commercially available cosmetic products and ask what lessons we can learn from them to enhance pharmaceutical microneedle product translation and commercialisation.<\/p>\n\n\n\n<p>We have known, for a long time, that the regulatory hurdles for pharmaceutical products are much greater than those for cosmetic products. Still, it&#8217;s interesting to see how cosmetic microneedle products have surged years (if not decades) ahead of their pharmaceutical counterparts, particularly in the Asian market. A low regulatory hurdle could spur innovation, but it could equally grow fad. How can one tell which it is? We examined a selection of commercially available cosmetic microneedle products to find out, and report our findings in this paper.<\/p>\n\n\n\n<p>This has been an interesting paper to work on. I have admired Goh&#8217;s tenacity collecting microneedle patches from pharmacies on his various international trips across Asia for this study. Last year, I <a href=\"https:\/\/x.com\/ngkengwooi\/status\/1865700101781344436\" data-type=\"link\" data-id=\"https:\/\/x.com\/ngkengwooi\/status\/1865700101781344436\" target=\"_blank\" rel=\"noreferrer noopener\">hosted him in Newcastle<\/a> to conduct parts of the study, including some microscopy work and the optical coherence tomography (OCT) analysis on microneedle penetration in ex vivo pig skin. It&#8217;s rewarding to see those efforts pay off.<\/p>\n\n\n\n<figure class=\"wp-block-embed is-type-rich is-provider-twitter wp-block-embed-twitter\"><div class=\"wp-block-embed__wrapper\">\n<blockquote class=\"twitter-tweet\" data-width=\"525\" data-dnt=\"true\"><p lang=\"en\" dir=\"ltr\">It was a pleasure to host <a href=\"https:\/\/twitter.com\/gohchoonfu?ref_src=twsrc%5Etfw\">@gohchoonfu<\/a> in <a href=\"https:\/\/twitter.com\/NCL_Pharmacy?ref_src=twsrc%5Etfw\">@NCL_pharmacy<\/a> <a href=\"https:\/\/twitter.com\/UniofNewcastle?ref_src=twsrc%5Etfw\">@UniofNewcastle<\/a> to work together on <a href=\"https:\/\/twitter.com\/hashtag\/microneedles?src=hash&amp;ref_src=twsrc%5Etfw\">#microneedles<\/a> in this international research collaboration. <a href=\"https:\/\/t.co\/ikm4tO2s6a\">https:\/\/t.co\/ikm4tO2s6a<\/a><\/p>&mdash; Keng Wooi Ng (@ngkengwooi) <a href=\"https:\/\/twitter.com\/ngkengwooi\/status\/1865700101781344436?ref_src=twsrc%5Etfw\">December 8, 2024<\/a><\/blockquote><script async src=\"\/\/platform.twitter.com\/widgets.js\" charset=\"utf-8\"><\/script>\n<\/div><\/figure>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Citation: Lee JY, Dong SH, Ng KW, Goh CF. Assessing the integrity and mechanical properties of commercial microneedles: innovation or fad? Drug Deliv Transl Res. 2025. doi: 10.1007\/s13346-025-01888-8 In this collaborative paper\u2014our second with the Malaysian team led by Dr Choon Fu Goh\u2014we examine some commercially available cosmetic products and ask what lessons we can &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/blogs.ncl.ac.uk\/kengng\/news\/assessing-the-integrity-and-mechanical-properties-of-commercial-microneedles-innovation-or-fad\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Assessing the integrity and mechanical properties of commercial microneedles: innovation or fad?&#8221;<\/span><\/a><\/p>\n","protected":false},"author":3965,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4,10],"tags":[75,17,7,22],"class_list":["post-1339","post","type-post","status-publish","format-standard","hentry","category-news","category-publications","tag-cosmetics","tag-drug-delivery","tag-microneedles","tag-skin"],"_links":{"self":[{"href":"https:\/\/blogs.ncl.ac.uk\/kengng\/wp-json\/wp\/v2\/posts\/1339","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.ncl.ac.uk\/kengng\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.ncl.ac.uk\/kengng\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.ncl.ac.uk\/kengng\/wp-json\/wp\/v2\/users\/3965"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.ncl.ac.uk\/kengng\/wp-json\/wp\/v2\/comments?post=1339"}],"version-history":[{"count":3,"href":"https:\/\/blogs.ncl.ac.uk\/kengng\/wp-json\/wp\/v2\/posts\/1339\/revisions"}],"predecessor-version":[{"id":1343,"href":"https:\/\/blogs.ncl.ac.uk\/kengng\/wp-json\/wp\/v2\/posts\/1339\/revisions\/1343"}],"wp:attachment":[{"href":"https:\/\/blogs.ncl.ac.uk\/kengng\/wp-json\/wp\/v2\/media?parent=1339"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.ncl.ac.uk\/kengng\/wp-json\/wp\/v2\/categories?post=1339"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.ncl.ac.uk\/kengng\/wp-json\/wp\/v2\/tags?post=1339"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}