{"id":9,"date":"2023-05-25T16:18:39","date_gmt":"2023-05-25T15:18:39","guid":{"rendered":"https:\/\/blogs.ncl.ac.uk\/painresearch\/?page_id=9"},"modified":"2024-11-15T17:01:27","modified_gmt":"2024-11-15T17:01:27","slug":"index","status":"publish","type":"page","link":"https:\/\/blogs.ncl.ac.uk\/painresearch\/","title":{"rendered":"Pain Research at Newcastle University"},"content":{"rendered":"\n<figure class=\"wp-block-image size-large is-style-default\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"695\" src=\"https:\/\/blogs.ncl.ac.uk\/painresearch\/files\/2023\/05\/61913-1024x695.jpg\" alt=\"\" class=\"wp-image-167\" srcset=\"https:\/\/blogs.ncl.ac.uk\/painresearch\/files\/2023\/05\/61913-1024x695.jpg 1024w, https:\/\/blogs.ncl.ac.uk\/painresearch\/files\/2023\/05\/61913-300x204.jpg 300w, https:\/\/blogs.ncl.ac.uk\/painresearch\/files\/2023\/05\/61913-768x521.jpg 768w, https:\/\/blogs.ncl.ac.uk\/painresearch\/files\/2023\/05\/61913-1536x1042.jpg 1536w, https:\/\/blogs.ncl.ac.uk\/painresearch\/files\/2023\/05\/61913-1200x814.jpg 1200w, https:\/\/blogs.ncl.ac.uk\/painresearch\/files\/2023\/05\/61913-1980x1343.jpg 1980w, https:\/\/blogs.ncl.ac.uk\/painresearch\/files\/2023\/05\/61913.jpg 1999w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<h2 class=\"wp-block-heading has-text-align-center has-accent-color has-text-color\">We explore the frontiers of pain to benefit patients<\/h2>\n\n\n\n<p class=\"has-text-align-center has-normal-font-size\">Our work crosses the disciplines of neuroscience, pharmacy, psychology, and clinical research to better understand and treat pain.<\/p>\n\n\n\n<div style=\"height:49px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><a href=\"https:\/\/blogs.ncl.ac.uk\/painresearch\/news\/\">Latest news<\/a><\/h2>\n\n\n\n<div class=\"wp-block-query is-layout-flow wp-block-query-is-layout-flow\"><ul class=\"wp-block-post-template is-layout-flow wp-block-post-template-is-layout-flow\"><li class=\"wp-block-post post-735 post type-post status-publish format-standard hentry category-news\">\n<h5 class=\"wp-block-post-title\"><a href=\"https:\/\/blogs.ncl.ac.uk\/painresearch\/emma-beecroft-invited-to-present-in-naples-italy-at-the-38th-international-aigedo-congress\/\" target=\"_self\" >Emma Beecroft invited to present In Naples, Italy at the 38th International AIGeDO Congress.\u00a0<\/a><\/h5>\n\n<div class=\"wp-block-post-excerpt\"><p class=\"wp-block-post-excerpt__excerpt\">Emma Beecroft was invited to speak in Naples, Italy, at the 38th International AIGeDO Congress on 10th October 2025. One of the core mission statements of the Italian Association for Gnathology and Orofacial Pain (AIGeDO) is to enhance practitioner expertise and patient care in this specialized field, making Emma&#8217;s invitation to present alongside eminent international&hellip;<\/p><p class=\"wp-block-post-excerpt__more-text\"><a class=\"wp-block-post-excerpt__more-link\" href=\"https:\/\/blogs.ncl.ac.uk\/painresearch\/emma-beecroft-invited-to-present-in-naples-italy-at-the-38th-international-aigedo-congress\/\">Read more<\/a><\/p><\/div>\n<\/li><li class=\"wp-block-post post-609 post type-post status-publish format-standard has-post-thumbnail hentry category-news\">\n<h5 class=\"wp-block-post-title\"><a href=\"https:\/\/blogs.ncl.ac.uk\/painresearch\/british-orthodontic-society-asm\/\" target=\"_self\" >British Orthodontic Society ASM<\/a><\/h5>\n\n<div class=\"wp-block-post-excerpt\"><p class=\"wp-block-post-excerpt__excerpt\">Justin was invited to present at this prestigious conference (16th Oct 2024) to discuss the management of TMD and the new guidelines available to help all healthcare professionals with TMD. He also explained some of the latest science behind changes in the mouth and face, pain pathways and central brain changes. His presentation can be&hellip;<\/p><p class=\"wp-block-post-excerpt__more-text\"><a class=\"wp-block-post-excerpt__more-link\" href=\"https:\/\/blogs.ncl.ac.uk\/painresearch\/british-orthodontic-society-asm\/\">Read more<\/a><\/p><\/div>\n<\/li><li class=\"wp-block-post post-554 post type-post status-publish format-standard has-post-thumbnail hentry category-news\">\n<h5 class=\"wp-block-post-title\"><a href=\"https:\/\/blogs.ncl.ac.uk\/painresearch\/team-present-work-at-world-endodontic-congress\/\" target=\"_self\" >Team present work at World Endodontic Congress in Glasgow<\/a><\/h5>\n\n<div class=\"wp-block-post-excerpt\"><p class=\"wp-block-post-excerpt__excerpt\">The team were well represented, with Professor Justin Durham, Dr Jamie Coulter, and Dr David Edwards presenting their research at the World Endodontic Congress held in in Glasgow in Sept 2024. Click here to access materials from this conference<\/p><p class=\"wp-block-post-excerpt__more-text\"><a class=\"wp-block-post-excerpt__more-link\" href=\"https:\/\/blogs.ncl.ac.uk\/painresearch\/team-present-work-at-world-endodontic-congress\/\">Read more<\/a><\/p><\/div>\n<\/li><\/ul><\/div>\n\n\n\n<div style=\"height:100px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><a href=\"https:\/\/blogs.ncl.ac.uk\/painresearch\/category\/research\/\">Current projects<\/a><\/h2>\n\n\n\n<div class=\"wp-block-query is-layout-flow wp-block-query-is-layout-flow\"><ul class=\"wp-block-post-template is-layout-flow wp-block-post-template-is-layout-flow\"><li class=\"wp-block-post post-594 post type-post status-publish format-standard hentry category-research\">\n<h5 class=\"wp-block-post-title\"><a href=\"https:\/\/blogs.ncl.ac.uk\/painresearch\/oldpain2go\/\" target=\"_blank\" >OldPain2Go<\/a><\/h5>\n\n<div class=\"wp-block-post-excerpt\"><p class=\"wp-block-post-excerpt__excerpt\">A randomised pilot virtual feasibility study for a virtual randomized control trial of a novel brief intervention for people with low back pain.<\/p><p class=\"wp-block-post-excerpt__more-text\"><a class=\"wp-block-post-excerpt__more-link\" href=\"https:\/\/blogs.ncl.ac.uk\/painresearch\/oldpain2go\/\">Read more<\/a><\/p><\/div>\n<\/li><li class=\"wp-block-post post-588 post type-post status-publish format-standard has-post-thumbnail hentry category-research\">\n<h5 class=\"wp-block-post-title\"><a href=\"https:\/\/blogs.ncl.ac.uk\/painresearch\/molecular-interplay-in-progression-of-neuropathic-pain-and-parkinsons-disease\/\" target=\"_blank\" >Molecular Interplay in Progression of Neuropathic pain and Parkinson&#8217;s Disease.<\/a><\/h5>\n\n<div class=\"wp-block-post-excerpt\"><p class=\"wp-block-post-excerpt__excerpt\">This study aims to identify the differential gene and protein expression associated with pain pathways in iPSCs-derived sensory neurons obtained from Parkinson&#8217;s patients or patients with TSC mutations vs iPSCs controls sensory neurons using genetic and proteins analyses. Then determining the functional abnormalities in patients\u2019 iPSC-derived sensory in response to pain stimuli by using functional [&hellip;]<\/p><p class=\"wp-block-post-excerpt__more-text\"><a class=\"wp-block-post-excerpt__more-link\" href=\"https:\/\/blogs.ncl.ac.uk\/painresearch\/molecular-interplay-in-progression-of-neuropathic-pain-and-parkinsons-disease\/\">Read more<\/a><\/p><\/div>\n<\/li><li class=\"wp-block-post post-592 post type-post status-publish format-standard hentry category-research\">\n<h5 class=\"wp-block-post-title\"><a href=\"https:\/\/blogs.ncl.ac.uk\/painresearch\/mediators-and-moderators-of-change-following-attendance-at-a-pain-management-programme\/\" target=\"_blank\" >Mediators and moderators of change following attendance at a Pain Management Programme<\/a><\/h5>\n\n<div class=\"wp-block-post-excerpt\"><p class=\"wp-block-post-excerpt__excerpt\">This study proposed an updated cognitive-behavioural model of persistent pain. Predicted relationships between variables informed by the model will be tested using multiple regression analyses, advancing our understanding of how psychological factors can be successfully targeted to improve clinical management of persistent pain.<\/p><p class=\"wp-block-post-excerpt__more-text\"><a class=\"wp-block-post-excerpt__more-link\" href=\"https:\/\/blogs.ncl.ac.uk\/painresearch\/mediators-and-moderators-of-change-following-attendance-at-a-pain-management-programme\/\">Read more<\/a><\/p><\/div>\n<\/li><li class=\"wp-block-post post-654 post type-post status-publish format-standard has-post-thumbnail hentry category-research\">\n<h5 class=\"wp-block-post-title\"><a href=\"https:\/\/blogs.ncl.ac.uk\/painresearch\/investigating-the-role-of-the-histamine-system-in-chronic-pain\/\" target=\"_blank\" >Investigating the role of the histamine system in chronic pain<\/a><\/h5>\n\n<div class=\"wp-block-post-excerpt\"><p class=\"wp-block-post-excerpt__excerpt\">Histamine, acting through all four types of histamine H1-H4 receptors, is arguably the most pleiotropic molecule in the human body. Since the cloning of H3R in 1999, there has been an increased interest within the pharmaceutical industry to discover and develop ligands to this receptor to target several diseases including neuropathic pain. However, while evidence [&hellip;]<\/p><p class=\"wp-block-post-excerpt__more-text\"><a class=\"wp-block-post-excerpt__more-link\" href=\"https:\/\/blogs.ncl.ac.uk\/painresearch\/investigating-the-role-of-the-histamine-system-in-chronic-pain\/\">Read more<\/a><\/p><\/div>\n<\/li><li class=\"wp-block-post post-724 post type-post status-publish format-standard hentry category-research\">\n<h5 class=\"wp-block-post-title\"><a href=\"https:\/\/blogs.ncl.ac.uk\/painresearch\/face-pd-facial-pain-experience-in-parkinsons-disease\/\" target=\"_blank\" >FacE-PD- Facial pain Experience in Parkinson\u2019s Disease\u00a0<\/a><\/h5>\n\n<div class=\"wp-block-post-excerpt\"><p class=\"wp-block-post-excerpt__excerpt\">This study aims to understand the types of pain affecting the face, head and mouth regions in people with Parkinson\u2019s disease. Most people living with Parkinson\u2019s disease experience pain, and this pain is often not well managed. Pain acts as the body\u2019s warning system, signalling that something may be wrong so that the area can [&hellip;]<\/p><p class=\"wp-block-post-excerpt__more-text\"><a class=\"wp-block-post-excerpt__more-link\" href=\"https:\/\/blogs.ncl.ac.uk\/painresearch\/face-pd-facial-pain-experience-in-parkinsons-disease\/\">Read more<\/a><\/p><\/div>\n<\/li><\/ul><\/div>\n\n\n\n<div style=\"height:71px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-1 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<h2 class=\"wp-block-heading alignwide has-text-align-center\">Our work is funded by<\/h2>\n\n\n\n<figure class=\"wp-block-gallery aligncenter has-nested-images columns-3 wp-block-gallery-1 is-layout-flex wp-block-gallery-is-layout-flex\">\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"1024\" src=\"https:\/\/blogs.ncl.ac.uk\/painresearch\/files\/2023\/05\/Wellcomne-Trans-1024x1024.png\" alt=\"\" class=\"wp-image-69\" srcset=\"https:\/\/blogs.ncl.ac.uk\/painresearch\/files\/2023\/05\/Wellcomne-Trans-1024x1024.png 1024w, https:\/\/blogs.ncl.ac.uk\/painresearch\/files\/2023\/05\/Wellcomne-Trans-300x300.png 300w, https:\/\/blogs.ncl.ac.uk\/painresearch\/files\/2023\/05\/Wellcomne-Trans-150x150.png 150w, https:\/\/blogs.ncl.ac.uk\/painresearch\/files\/2023\/05\/Wellcomne-Trans-768x768.png 768w, https:\/\/blogs.ncl.ac.uk\/painresearch\/files\/2023\/05\/Wellcomne-Trans.png 1200w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"242\" src=\"https:\/\/blogs.ncl.ac.uk\/painresearch\/files\/2023\/05\/National-Institute-for-Health-Research_logo_outlined_RGB_COL-2-1024x242.png\" alt=\"\" class=\"wp-image-63\" srcset=\"https:\/\/blogs.ncl.ac.uk\/painresearch\/files\/2023\/05\/National-Institute-for-Health-Research_logo_outlined_RGB_COL-2-1024x242.png 1024w, https:\/\/blogs.ncl.ac.uk\/painresearch\/files\/2023\/05\/National-Institute-for-Health-Research_logo_outlined_RGB_COL-2-300x71.png 300w, https:\/\/blogs.ncl.ac.uk\/painresearch\/files\/2023\/05\/National-Institute-for-Health-Research_logo_outlined_RGB_COL-2-768x181.png 768w, https:\/\/blogs.ncl.ac.uk\/painresearch\/files\/2023\/05\/National-Institute-for-Health-Research_logo_outlined_RGB_COL-2-1200x283.png 1200w, https:\/\/blogs.ncl.ac.uk\/painresearch\/files\/2023\/05\/National-Institute-for-Health-Research_logo_outlined_RGB_COL-2.png 1250w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"490\" height=\"408\" src=\"https:\/\/blogs.ncl.ac.uk\/painresearch\/files\/2023\/05\/ukri-mrc-square-logo.png\" alt=\"\" class=\"wp-image-68\" srcset=\"https:\/\/blogs.ncl.ac.uk\/painresearch\/files\/2023\/05\/ukri-mrc-square-logo.png 490w, https:\/\/blogs.ncl.ac.uk\/painresearch\/files\/2023\/05\/ukri-mrc-square-logo-300x250.png 300w\" sizes=\"auto, (max-width: 490px) 100vw, 490px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"715\" height=\"332\" src=\"https:\/\/blogs.ncl.ac.uk\/painresearch\/files\/2023\/05\/FDS-Trans.png\" alt=\"\" class=\"wp-image-65\" srcset=\"https:\/\/blogs.ncl.ac.uk\/painresearch\/files\/2023\/05\/FDS-Trans.png 715w, https:\/\/blogs.ncl.ac.uk\/painresearch\/files\/2023\/05\/FDS-Trans-300x139.png 300w\" sizes=\"auto, (max-width: 715px) 100vw, 715px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"680\" height=\"680\" src=\"https:\/\/blogs.ncl.ac.uk\/painresearch\/files\/2023\/05\/MEUK-trans.png\" alt=\"\" class=\"wp-image-64\" srcset=\"https:\/\/blogs.ncl.ac.uk\/painresearch\/files\/2023\/05\/MEUK-trans.png 680w, https:\/\/blogs.ncl.ac.uk\/painresearch\/files\/2023\/05\/MEUK-trans-300x300.png 300w, https:\/\/blogs.ncl.ac.uk\/painresearch\/files\/2023\/05\/MEUK-trans-150x150.png 150w\" sizes=\"auto, (max-width: 680px) 100vw, 680px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"135\" height=\"157\" src=\"https:\/\/blogs.ncl.ac.uk\/painresearch\/files\/2023\/05\/Picture1.png\" alt=\"\" class=\"wp-image-67\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1000\" height=\"230\" src=\"https:\/\/blogs.ncl.ac.uk\/painresearch\/files\/2023\/05\/HEE.png\" alt=\"\" class=\"wp-image-70\" srcset=\"https:\/\/blogs.ncl.ac.uk\/painresearch\/files\/2023\/05\/HEE.png 1000w, https:\/\/blogs.ncl.ac.uk\/painresearch\/files\/2023\/05\/HEE-300x69.png 300w, https:\/\/blogs.ncl.ac.uk\/painresearch\/files\/2023\/05\/HEE-768x177.png 768w\" sizes=\"auto, (max-width: 1000px) 100vw, 1000px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"326\" height=\"155\" src=\"https:\/\/blogs.ncl.ac.uk\/painresearch\/files\/2023\/05\/download.png\" alt=\"\" class=\"wp-image-71\" srcset=\"https:\/\/blogs.ncl.ac.uk\/painresearch\/files\/2023\/05\/download.png 326w, https:\/\/blogs.ncl.ac.uk\/painresearch\/files\/2023\/05\/download-300x143.png 300w\" sizes=\"auto, (max-width: 326px) 100vw, 326px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"596\" height=\"169\" src=\"https:\/\/blogs.ncl.ac.uk\/painresearch\/files\/2023\/05\/64192.png\" alt=\"\" class=\"wp-image-72\" srcset=\"https:\/\/blogs.ncl.ac.uk\/painresearch\/files\/2023\/05\/64192.png 596w, https:\/\/blogs.ncl.ac.uk\/painresearch\/files\/2023\/05\/64192-300x85.png 300w\" sizes=\"auto, (max-width: 596px) 100vw, 596px\" \/><\/figure>\n<\/figure>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>We explore the frontiers of pain to benefit patients Our work crosses the disciplines of neuroscience, pharmacy, psychology, and clinical research to better understand and treat pain. Latest news Current projects Our work is funded by<\/p>\n","protected":false},"author":8160,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-9","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/blogs.ncl.ac.uk\/painresearch\/wp-json\/wp\/v2\/pages\/9","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.ncl.ac.uk\/painresearch\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/blogs.ncl.ac.uk\/painresearch\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.ncl.ac.uk\/painresearch\/wp-json\/wp\/v2\/users\/8160"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.ncl.ac.uk\/painresearch\/wp-json\/wp\/v2\/comments?post=9"}],"version-history":[{"count":52,"href":"https:\/\/blogs.ncl.ac.uk\/painresearch\/wp-json\/wp\/v2\/pages\/9\/revisions"}],"predecessor-version":[{"id":672,"href":"https:\/\/blogs.ncl.ac.uk\/painresearch\/wp-json\/wp\/v2\/pages\/9\/revisions\/672"}],"wp:attachment":[{"href":"https:\/\/blogs.ncl.ac.uk\/painresearch\/wp-json\/wp\/v2\/media?parent=9"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}