{"id":599,"date":"2017-03-30T12:42:34","date_gmt":"2017-03-30T11:42:34","guid":{"rendered":"https:\/\/blogs.ncl.ac.uk\/katarzynapirog\/?page_id=599"},"modified":"2026-03-19T11:52:53","modified_gmt":"2026-03-19T11:52:53","slug":"list-of-labs-publications","status":"publish","type":"page","link":"https:\/\/blogs.ncl.ac.uk\/piroglab\/list-of-labs-publications\/","title":{"rendered":"List of lab&#8217;s publications"},"content":{"rendered":"\n<ul class=\"wp-block-list\">\n<li>Hao Y, Lin H, Soul J, Overman LM, Lisgo SN, Coxhead J,\u00a0 <strong>Pir\u00f3g KA<\/strong>, \u00a0Clark IM, Barter MJ,\u00a0 Reynard LN, Young DA. <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1063458425012294?via%3Dihub\">Transcriptomic profiling confirms microRNA-140 is more functional in cartilage development than osteoarthritis.<\/a> Osteoarthritis and Cartilage, 2026, https:\/\/doi.org\/10.1016\/j.joca.2025.11.005.<\/li>\n\n\n\n<li><strong>Farcasanu M*, de las Heras Ruiz T*, Johnson de Sousa Brito FM<\/strong>, Soul J, Coxhead J, German M, Young DA, Ferreira-Duarte A, <strong>Pir\u00f3g KA<\/strong>. <a href=\"https:\/\/doi.org\/10.1002\/bit.29026\">Dynamic compression improves chondrogenesis in the tissue engineered model of cartilage.<\/a> Biotechnology and Bioengineering 2025; 122: 2574-2591.<\/li>\n\n\n\n<li>Hayman DJ, <strong>Johnson de Sousa Brito FM<\/strong>, Lin H, Prior A, Charlesworth G, Hao Y, <strong>Pearson RD<\/strong>, Soul J, Clark IM, <strong>Pir\u00f3g KA<\/strong>, Barter MJ, Van&#8217;t Hof RJ, Young DA. <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S875632822400262X?utm_campaign=STMJ_219742_AUTH_SERV_PA&amp;utm_medium=email&amp;utm_acid=125753579&amp;SIS_ID=&amp;dgcid=STMJ_219742_AUTH_SERV_PA&amp;CMX_ID=&amp;utm_in=DM513790&amp;utm_source=AC_\">microRNA-324 mediates bone homeostasis and the regulation of osteoblast and osteoclast differentiation and activity<\/a>. Bone, 2025; 190, 117273.<\/li>\n\n\n\n<li><strong>Johnson de Sousa Brito FM<\/strong>,&nbsp;<strong>Pearson RD<\/strong>, Kalamajski S,&nbsp;Young DA, <strong>Pirog KA<\/strong>. <a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/epdf\/10.1111\/iep.12512?saml_referrer\">Role of Asporin in chondroprotection<\/a>. Int J Exp Path 2024;105:A1\u2013A23<\/li>\n\n\n\n<li><strong>Bouchenafa R, Ben-Tiba E, Johnson de Sousa Brito FM, Pirog KA<\/strong>. <a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/epdf\/10.1111\/iep.12512?saml_referrer\">Pro143Leu KIF22 mutation affect cartilage structure in the SEMDJL2 mice<\/a>. Int J Exp Path 2024;105:A1\u2013A23<\/li>\n\n\n\n<li><strong>Farcasanu M, de las Heras Ruiz T, Pir\u00f3g KA. <\/strong><a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/epdf\/10.1111\/iep.12512?saml_referrer\">Dynamic mechanical compression improves the chondrogenic potential of ATDC5 and primary human chondrocytes in agar hydrogels.<\/a>  Int J Exp Path 2024;105:A1\u2013A23<\/li>\n\n\n\n<li><strong>Johnson de Sousa Brito FM, Bouchenafa R, Pearson RD, Pirog KA.<\/strong> <em><a href=\"https:\/\/link.springer.com\/chapter\/10.1007\/978-3-031-70835-0_11\" data-type=\"link\" data-id=\"https:\/\/link.springer.com\/chapter\/10.1007\/978-3-031-70835-0_11\">Microtubule-associated motor proteins in skeletal development and health<\/a><\/em>, 2024. In: Rossi, A., Zaucke, F. (eds) The Extracellular Matrix in Genetic Skeletal Disorders. Biology of Extracellular Matrix, vol 16. Springer, Cham. https:\/\/doi.org\/10.1007\/978-3-031-70835-0_11.<\/li>\n\n\n\n<li>Gilbert SJ, Soul J, Hao Y, Lin H, <strong> Pir\u00f3g KA<\/strong>, Coxhead J, Patel K, Barter MJ, Young DA, Blain EJ. <a href=\"https:\/\/journals.biologists.com\/dmm\/article\/doi\/10.1242\/dmm.050583\/362126\/Comparative-transcriptomic-analysis-of-articular?searchresult=1\">Comparative transcriptomic analysis of articular cartilage of post-traumatic osteoarthritis mouse models<\/a>. Dis Model Mech, 2024; 17(10): dmm050583.<\/li>\n\n\n\n<li><strong>Bouchenafa R, Johnson de Sousa Brito FM, Pirog KA.<\/strong><a href=\"https:\/\/journals.physiology.org\/doi\/abs\/10.1152\/ajpcell.00613.2023\" data-type=\"link\" data-id=\"https:\/\/journals.physiology.org\/doi\/abs\/10.1152\/ajpcell.00613.2023\"> Involvement of kinesins in skeletal dysplasia \u2013 a review<\/a>. 2024 Apr 22.&nbsp;doi: 10.1152\/ajpcell.00613.2023. Online ahead of print.<\/li>\n\n\n\n<li><strong>de las Heras Ruiz T, Johnson de Sousa Brito FM, Farcasanu M, Howe S,<\/strong>&nbsp;Young D,&nbsp;<strong>Pirog KA<\/strong>. <a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/epdf\/10.1111\/iep.12421\">Dynamic compression dramatically improves the chondrogenic potential of ATDC5 cells in the tissue engineered model of healthy and PSACH cartilage.<\/a>&nbsp;Int J Exp Path. 2022;103:A1\u2013A14.<\/li>\n\n\n\n<li>Hayman DJ, Modebadze T, Charlton S, Cheung K, Soul J, Lin H, Hao Y, Miles CG, Tsompani D, Jackson RM, Briggs MD, <strong>Pirog KA<\/strong>, Clark IM, Barter MJ, Clowry GJ, LeBeau FEN &amp; Young DA. <a href=\"https:\/\/www.nature.com\/articles\/s41598-021-89874-1.epdf?sharing_token=SOgldReXH2B2172JpSaru9RgN0jAjWel9jnR3ZoTv0PdtTIbEJEMw3KNQYejIDQPBFGkdpYRMwB1k6GrzWaMhpH-x1eBfoWTXHBPrKoboFrRgKTAMSpWJlmP22V9YZTyPiGJ7h8KNOL_B4LtvB1eqDkLN6L4qZ76nNcF3FoU7yD-oet7OOLt1siOlkdT3Ysf\">Increased hippocampal excitability in miR\u2011324\u2011null mice.<\/a> <em>Scientific Reports<\/em> 2021, 11:10452<\/li>\n\n\n\n<li><strong>Dennis<\/strong> <strong>EP<\/strong>,&nbsp;<strong>Johnson de Sousa Brito FM<\/strong>,&nbsp;<strong>Pearson RD<\/strong>, Jackson RM, Logan J, Capulli M,  Teti A, Duncan Bassett JH, Williams GR, Kalamajski S,&nbsp;<strong>Pirog KA<\/strong>.&nbsp;<a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/epdf\/10.1111\/iep.12409\">Asporin is important in bone development but not in cartilage homeostasis.<\/a>&nbsp;Int J Exp Path. 2021;102:A1\u2013A17.<\/li>\n\n\n\n<li>Woods S, Charlton S,  Cheung K, Hao Y, Soul J,  Reynard LN,  Crowe N, Swingler TE,  Skelton AJ,  <strong>Pirog KA<\/strong>,  Miles CG,  Tsompani D,  Jackson RM, Dalmay T,  Clark IM,  Barter MJ,  Young DA. <a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2020.01.29.925206v1\">microRNA-seq of cartilage reveals an over-abundance of miR-140-3p which contains functional isomiRs<\/a> <em>RNA<\/em> 2020, 26(11):1575-1588.<\/li>\n\n\n\n<li>Briggs MD, <strong>Dennis EP<\/strong>, Dietmar H, <strong>Pirog KA<\/strong>. <a href=\"https:\/\/doi.org\/10.12688\/f1000research.22275.1\">New developments in chondrocyte ER-stress and related diseases. <\/a><em> F1000Research<\/em> 2020, 9 (F1000 Faculty Rev):290 <\/li>\n\n\n\n<li><strong>Dennis EP<\/strong>, Edwards S, Jackson RM, Capulli M, Teti A, Ishiguro K, <strong>Pirog KA<\/strong>,  Briggs MD. <a href=\"https:\/\/asbmr.onlinelibrary.wiley.com\/doi\/abs\/10.1002\/jbmr.4010\">CRELD2 is a novel LRP1 chaperone that regulates non-canonical  WNT signalling in skeletal development.<\/a><em> JBMR<\/em>  2020, 35 (8):1452-1469<\/li>\n\n\n\n<li><strong>Pir\u00f3g KA<\/strong>, <strong>Dennis EP<\/strong>, Hartley CL, Jackson RM, Soul J, Schwartz JM, Bateman JF, Boot-Handford RP, Briggs MD.&nbsp;<a href=\"https:\/\/eprint.ncl.ac.uk\/258276\">XBP1 signalling is essential for alleviating mutant protein aggregation in ER-stress related skeletal disease<\/a>.&nbsp;<em>PLoS Genetics<\/em>&nbsp;2019,&nbsp;<strong>15<\/strong>(7), e1008215.<\/li>\n\n\n\n<li>Paganini C, Monti L, Costantini R, Besio R, Lecci S, Biggiogera M, Tian K, Schwartz JM, Huber C, Cormier-Daire V, <strong>Gibson BG<\/strong>, <strong>Pirog KA<\/strong>, Forlino A, Rossi A. <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0945053X18303974?via%3Dihub\">Calcium  activated nucleotidase 1 (CANT1) is critical for glycosaminoglycan  biosynthesis in cartilage and endochondral ossification.<\/a> <em>Matrix Biol<\/em>o<em>gy<\/em> 2018, pii: S0945-053X(18)30397-4.<\/li>\n\n\n\n<li>Briggs MD, Bell PA, <strong>Pirog KA<\/strong>. <a href=\"http:\/\/www.springer.com\/gb\/book\/9783319458014\">Pseudoachondroplasia and Multiple Epiphyseal Dysplasia: Molecular Genetics, Disease Mechanisms and Therapeutic Targets<\/a>. <em>In: Cartilage, Volume 2: Pathophysiology.<\/em> Springer International Publishing AG, 2017.<\/li>\n\n\n\n<li><strong>de-las-Heras-Ruiz T<\/strong>, <strong>Pirog KA<\/strong>. <a href=\"http:\/\/www.smgebooks.com\/osteoarthritis\/chapters\/OAS-16-08.pdf\">Tissue Engineering Approaches for the Study and Therapeutic Intervention in Osteoarthritis<\/a>. <em>In: Osteoarthritis<\/em>. SM Group Open Access eBooks, 2016.<\/li>\n\n\n\n<li><strong>Dennis EP<\/strong>, Capulli M, Teti A,<strong> Pirog KA<\/strong>, Briggs MD.&nbsp;<a href=\"https:\/\/eprint.ncl.ac.uk\/275460\">The role of Creld2 in skeletal development and homeostasis<\/a>.&nbsp;<em>In: 43rd Annual European Calcified Tissue Society Congress<\/em>. 2016, Rome, Italy: Bone Abstracts.<\/li>\n\n\n\n<li><strong>Gibson BG<\/strong>, Sonntag S, Selbert S, <strong>Pirog KA<\/strong>, Briggs MD.&nbsp;<a href=\"https:\/\/eprint.ncl.ac.uk\/232544\">Transgenic mice with an allelic series of aggrecan mutations model the human phenotypes<\/a>.&nbsp;<em>In: British Society for Matrix Biology \/ Bone Research Society Third Joint Meeting<\/em>. 2015, Edinburgh: Wiley-Blackwell Publishing Ltd.<\/li>\n\n\n\n<li>Cameron TL, Gresshoff IL, Bell KM, <strong>Pirog KA<\/strong>, Sampurno L, Hartley CL, Sanford EM, Wilson R, Ermann J, Boot-Handford RP, Glimcher LH, Briggs MD, Bateman JF. <a href=\"http:\/\/www.oarsijournal.com\/article\/S1063-4584(15)00004-7\/pdf\">Cartilage-Specific  Ablation of XBP1 Signaling in Mouse Results in a Chondrodysplasia  Characterized by Reduced Chondrocyte Proliferation and Delayed Cartilage  Maturation and Mineralization<\/a>. <em>Osteoarthritis and Cartilage<\/em> 2015, 23, 661-670.<\/li>\n\n\n\n<li>Briggs MD, Bell PA, Wright MJ, <strong>Pirog KA<\/strong>. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4643203\/pdf\/ieod-3-1137.pdf\">New therapeutic targets in rare genetic skeletal diseases<\/a>. <em>Expert Opinion on Orphan Drugs<\/em> 2015, 3(10), 1137-1154.<\/li>\n\n\n\n<li>Briggs MD, Bell PA, <strong>Pirog KA<\/strong>. <a href=\"http:\/\/eprint.ncl.ac.uk\/file_store\/production\/211926\/7ECB2624-7B4D-49B5-AFD3-7C22C4689A14.pdf\">The  utility of mouse models to provide information regarding the  pathomolecular mechanisms in human genetic skeletal diseases: The  emerging role of endoplasmic reticulum stress (Review)<\/a>. <em>International Journal of Molecular Medicine<\/em> 2015, 1483-1492.<\/li>\n\n\n\n<li><strong>Pirog KA<\/strong>, Irman A, Young S, Halai P, Bell PA, Boot-Handford RP, Briggs MD. <a href=\"http:\/\/journals.plos.org\/plosone\/article\/file?id=10.1371\/journal.pone.0085145&amp;type=printable\">Abnormal  Chondrocyte Apoptosis in the Cartilage Growth Plate is Influenced by  Genetic Background and Deletion of CHOP in a Targeted Mouse Model of  Pseudoachondroplasia<\/a>. <em>PLoS One<\/em> 2014, 9(2), e85145.<\/li>\n\n\n\n<li><strong>Pirog KA<\/strong>, Katakura Y, Mironov A, Briggs MD. <a href=\"http:\/\/journals.plos.org\/plosone\/article\/file?id=10.1371\/journal.pone.0082412&amp;type=printable\">Mild myopathy is associated with COMP but not MATN3 mutations in mouse models of genetic skeletal diseases<\/a>. <em>PLoS One<\/em> 2013, 8(11), e82412.<\/li>\n\n\n\n<li><strong>Pirog KA<\/strong>, Meadows RS, Boot-Handford RP, Briggs MD. <a href=\"https:\/\/mikebriggs1910.files.wordpress.com\/2013\/09\/bsmb-abstract_kpirog.pdf\">Mutant  chondrocytes are characterised by altered cell shape and changes to the  organisation of primary cilia in a genetic mouse model of mild  pseudoachondroplasia<\/a>. <em>In: British Society for Matrix Biology Autumn 2013 Meeting<\/em>. 2013, Cardiff: Wiley-Blackwell.<\/li>\n\n\n\n<li>Suleman F, Gualeni B, Gregson HJ, Leighton MP,<strong> Pirog KA<\/strong>, Edwards S, Holden P, Boot-Handford RP, Briggs MD. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3320758\/pdf\/humu0033-0218.pdf\">A novel form of chondrocyte stress is triggered by a COMP mutation causing pseudoachondroplasia<\/a>. <em>Human Mutation<\/em> 2012, 33(1), 218-231.<\/li>\n\n\n\n<li>Bell PA, <strong>Pirog KA<\/strong>, Fresquet M, Thornton DJ, Boot-Handford RP, Briggs MD. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3374853\/pdf\/art0064-1529.pdf\">Loss of matrilin 1 does not exacerbate the skeletal phenotype in a mouse model of multiple epiphyseal dysplasia caused by a <em>Matn3<\/em> V194D mutation<\/a>. <em>Arthritis &amp; Rheumatism<\/em> 2012, 64(5), 1529-1539.<\/li>\n\n\n\n<li><strong>Pirog KA<\/strong>, Jaka O, Katakura Y, Meadows RS, Kadler KE, Boot-Handford RP, Briggs MD. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2792148\/pdf\/ddp466.pdf\">A  mouse model offers novel insights into the myopathy and tendinopathy  often associated with pseudoachondroplasia and multiple epiphyseal  dysplasia<\/a>. <em>Human Molecular Genetics<\/em> 2010, 19(1), 52-64.<\/li>\n\n\n\n<li><strong>Pirog KA<\/strong>, Briggs MD. <a href=\"https:\/\/www.hindawi.com\/journals\/bmri\/2010\/686457\/\">Skeletal Dysplasias Associated with Mild Myopathy-A Clinical and Molecular Review<\/a>. <em>Journal of Biomedicine and Biotechnology<\/em> 2010, Article no. 686457.<\/li>\n\n\n\n<li><strong>Pirog-Garcia KA<\/strong>, Meadows RS, Knowles L, Heinegard D, Thornton DJ, Kadler KE, Boot-Handford RP, Briggs MD. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2674228\/pdf\/ukmss-4443.pdf\">Reduced  cell proliferation and increased apoptosis are significant pathological  mechanisms in a murine model of mild pseudoachondroplasia resulting  from a mutation in the C-terminal domain of COMP<\/a>. <em>Human Molecular Genetics<\/em> 2007, 16(17), 2072-2088.<\/li>\n\n\n\n<li><strong>Pirog KA<\/strong>, Kowalczyk AK, Rokita HB. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/15802967\">Changes in <em>Bcl-2<\/em> expression in vaccinia virus-infected human peripheral blood monocytes<\/a>. <em>Viral Immunology<\/em> 2005, 18(1), 224-231.<\/li>\n\n\n\n<li><strong>Pirog KA<\/strong>. <em><a href=\"http:\/\/nukat.edu.pl\/lib\/item?id=chamo:73490&amp;theme=nukat\">Terapia genowa (Gene therapy)<\/a>.<\/em> Wydaw: Jagiellonian University Press, 2002.<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":4483,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-599","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/blogs.ncl.ac.uk\/piroglab\/wp-json\/wp\/v2\/pages\/599","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.ncl.ac.uk\/piroglab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/blogs.ncl.ac.uk\/piroglab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.ncl.ac.uk\/piroglab\/wp-json\/wp\/v2\/users\/4483"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.ncl.ac.uk\/piroglab\/wp-json\/wp\/v2\/comments?post=599"}],"version-history":[{"count":54,"href":"https:\/\/blogs.ncl.ac.uk\/piroglab\/wp-json\/wp\/v2\/pages\/599\/revisions"}],"predecessor-version":[{"id":2749,"href":"https:\/\/blogs.ncl.ac.uk\/piroglab\/wp-json\/wp\/v2\/pages\/599\/revisions\/2749"}],"wp:attachment":[{"href":"https:\/\/blogs.ncl.ac.uk\/piroglab\/wp-json\/wp\/v2\/media?parent=599"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}