Publications – Rebecca P Payne

2018

Single-cell reconstruction of the early maternal–fetal interface in humans. Vento-Tormo R, Efremova M, Turco M, Botting R, Meyer K, Park J, Stephenson E, Payne RP, Goncalves A, Zou A, Henriksson J, Wood L, Lisgo S, Filby A, Wright G, Stubbington M, Haniffa M, Moffett A, Teichmann SA. Nature. 2018 Nov;563(7731):347-353

2015

Reply to Jefferys: Declining HIV Virulence. Payne RP, Muenchhoff M, Goulder PJR. PNAS 2015 Mar Letter (online only)

2014

Impact of HLA-driven HIV adaptation and of anti-retroviral therapy on HIV virulence. Payne RP, Muenchhoff M, Mann J, Roberts HE, Matthews P, Adland E, Hempenstall A, Huang KH, Brockman M, Brumme Z, Sinclair M, Miura T, Frater J, Essex M, Shapiro R, Walker BD, Ndung’u T, McLean AR, Carlson JM, Goulder PJR. PNAS 2014 Dec 16;111(50):E5393-400

This paper showed that HIV is weakening over time.

Impact of HLA Selection Pressure on HIV Fitness at a Population Level in Mexico and Barbados. Juarez-Molina CI, Payne R, Soto-Nava M, et al. Journal of Virology 2014 Sep 15;88(18):10392-8
Differential escape patterns within the dominant HLA-B*57:03-restricted HIV Gag epitope reflect distinct clade-specific functional constraints. Payne RP, Branch S, Kløverpris H, Matthews PC et al. Journal of Virology 2014 May;88(9):4668-78

2013

HLA-specific intracellular epitope processing shapes an immunodominance pattern for HLA-B*57 that is distinct from HLA-B*58:01. Kløverpris HN, Stryhn A, Harndahl M, Payne R, et al. Journal of Virology 2013 Oct;87(19):10889-94
Early antigen presentation of protective HIV-1 KF11_Gag and KK10_Gag epitopes from incoming viral particles facilitates rapid recognition of infected cells by specific CD8+ T cells. Kløverpris H, Payne RP, Sacha JB, Rasaiyaah JT, et al. Journal of Virology. 2013 Mar;87(5):2628-38

2012

Co-operative additive effect between HLA alleles in control of HIV-1 viraemia is linked to breadth of CD8+ T cell responses. Matthews P, Listgarten J, Carlson J, Payne RP, Huang KH, et al. PLoS One. 2012;7(10)
Differential clade-specific HLA-B*3501 association with HIV-1 disease outcome is linked to immunogenicity of a single Gag epitope. Matthews PC*, Koyanagi M*,Kloverpris HN *, Harndahl M, Stryhn A, Gatanaga H, Oka S, Molina CJ, Ponce HV, Rios SA, Cole D, Carlson J, Payne RP, et al. Journal of Virology: 2012 Dec;86(23):12643-54
HLA-B*57 Micropolymorphism shapes HLA allele-specific epitope immunongenicity, selection pressure , and HIV immune control. Kloverpris HN, Stryhn A, Harndahl M, van der Stok M, Payne RP, et al. J Virol. 2012 Jan;86(2):919-29.

Pre-2012

HLA-A*7401-mediated control of HIV viraemia is independent of its linkage disequilibrium with HLA-B*5703. Matthews PC, Adland E, Listgarten J, Leslie A, Mkhwanazi N, Harndahl M, Payne RP, et al. J Immunol. 2011 May 15;186(10):5675-86
Efficacious early antiviral activity of HIV Gag- and Pol-specific HLA-B*2705-restricted CD8⁺ T-cells. Payne RP, Kløverpris H, Sacha JB, et al. Journal of Virology:2010; 84(20)-10543-57

HLA-mediated control of HIV and HIV adaptation to HLA. Payne RP*, Matthews PC, Prado JG, Goulder PJ. Advances in Parasitology, 2009; 58:1-20 (Review)
HLA footprints on human immunodeficiency virus type 1 are associated with Interclade Polymorphisms and Intraclade Phylogenetic Clustering

Adaptation of HIV-1 to human leukocyte antigen class I. Kawashima Y, Pfafferott K, Frater J, Matthews P, Payne R*, et al. Nature, 2009 Apr 2;458(7238):641-5

Central role of reverting mutations in HLA associations with human immunodeficiency virus set point. Matthews PC, Prendergast A, Leslie A, Crawford H, Payne R, et al. Journal of Virology, 2008 Sep;82(17):8548-59.
HLA class I-driven evolution of human immunodeficiency virus type I subtype c proteome: immune escape and viral load. Rousseau CM, Daniels MG, Carlson JM, Kadie C, Crawford H, Prendergast A, Matthews P, Payne R, et al. Journal of Virology. 2008 Jul;82(13):6434-46
Effective T-cell responses select human immunodeficiency virus mutants and slow disease progression. Frater AJ, Brown H, Oxenius A, Günthard HF, Hirschel B, Robinson N, Leslie AJ, Payne R et al. Journal of Virology, 2007 Jun;81(12):6742-51
Control of human immunodeficiency virus type 1 is associated with HLA-B*13 and targeting of multiple gag-specific CD8+ T-cell epitopes. Honeyborne I, Prendergast A, Pereyra F, Leslie A, Crawford H, Payne R et al. Journal of Virology. 2007 Apr;81(7):3667-72.

CD8+ T-cell responses to different HIV proteins have discordant associations with viral load. Kiepiela P, Ngumbela K, Thobakgale C, Ramduth D, Honeyborne I, Moodley E, Reddy S, de Pierres C, Mncube Z, Mkhwanazi N, Bishop K, van der Stok M, Nair K, Khan N, Crawford H, Payne R, et al. Nature Medicine. 2007 Jan;13(1):46-53