Publications

Pentamethylphenyl (Ph*) ketones: Unique building blocks for organic synthesis

Roly J. Armstrong and Timothy J. Donohoe

Tetrahedron Lett. 2021, 74, 153151 (DOI: 10.1016/j.tetlet.2021.153151)


Control of Absolute Stereochemistry in Transition-Metal-Catalyzed Hydrogen Borrowing Reactions

Timothy Kwok, Oskar Hoff, Roly J. Armstrong and Timothy J. Donohoe

Chem. Eur. J. 2020, 26, 12912 (DOI: 10.1002/chem.202001253)


Enantioconvergent Alkylation of Ketones with Racemic Secondary Alcohols via Hydrogen Borrowing Catalysis

Daniella M. J. Cheang, Roly J. Armstrong, Wasim M. Akhtar, and Timothy J. Donohoe

Chem. Commun. 2020, 56, 3543 (DOI: 10.1039/D0CC00767F)


Chemo- and Regioselective Synthesis of Acyl-Cyclohexenes by a Tandem Acceptorless Dehydrogenation-[1,5]-Hydride Shift Cascade

Lewis B. Smith, Roly J. Armstrong, Daniel Matheau-Raven and Timothy J. Donohoe

J. Am. Chem. Soc. 2020, 142, 2514 (DOI: 10.1021/jacs.9b12296)


A Hydrogen Borrowing Annulation Strategy for the Stereocontrolled Synthesis of Saturated Aza-Heterocycles

Anna E. R. Chamberlain, Kieran J. Paterson, Roly J. Armstrong, Heather C. Twin, and Timothy J. Donohoe

Chem. Commun. 2020, 56, 3563 (DOI: 10.1039/D0CC00903B)


Synthesis of Allenes by 1,2-Elimination

Roly J. Armstrong

Curr. Org. Chem. 2019, 23, 3027 (DOI: 10.2174/1385272823666191121122011)


Catalytic Asymmetric Synthesis of Cyclohexanes by Hydrogen Borrowing Annulations

Roly J. Armstrong, Wasim M. Akhtar, Tom A. Young, Fernanda Duarte and Timothy J. Donohoe

Angew. Chem. Int. Ed. 2019, 58, 12558 (DOI: 10.1002/anie.201907514)


Stereoselective Synthesis of Alicyclic Ketones: a Hydrogen Borrowing Approach

Roly J. Armstrong, Wasim M. Akhtar, James R. Frost, Neil G. Stevenson and Timothy J. Donohoe

Tetrahedron 2019, 75, 130680 (DOI: 10.1016/j.tet.2019.130680)


Stereoselective Synthesis of Cyclohexanes via an Iridium Catalyzed (5 + 1) Annulation Strategy,

Wasim M. Akhtar, Roly J. Armstrong, James R. Frost, Neil G. Stevenson and Timothy J. Donohoe

J. Am. Chem. Soc. 2018, 140, 11916 (DOI: 10.1021/jacs.8b07776)


Enantiodivergent Synthesis of Allenes by Point to Axial Chirality Transfer

Roly J. Armstrong, Meganathan Nandakumar, Rafael M. P. Dias, Adam Noble, Eddie L. Myers and Varinder K. Aggarwal

Angew. Chem. Int. Ed. 2018, 57, 8203 (DOI: 10.1002/anie.201804446)


50 Years of Zweifel Olefination: a Transition-Metal-Free Coupling

Roly J. Armstrong and Varinder K. Aggarwal

Synthesis 2017, 49, 3323 (DOI: 10.1055/s-0036-1589046)


Stereodivergent Olefination of Enantioenriched Boronic Esters

Roly J. Armstrong, Cristina García-Ruiz, Eddie L. Myers, and Varinder K. Aggarwal

Angew. Chem. Int. Ed. 2017, 56, 786 (DOI: 10.1002/anie.201610387)


Conjunctive Functionalization of Vinyl Boronate Complexes with Electrophiles: A Diastereoselective Three-Component Coupling

Roly J. Armstrong, Christopher Sandford, Cristina García-Ruiz and Varinder K. Aggarwal

Chem. Commun. 2017, 53, 4922 (DOI: 10.1039/C7CC01671A)


Synthesis of Functionalized Alkenes by a Transition-Metal-Free Zweifel Coupling

Roly J. Armstrong, Worawat Niwetmarin and Varinder K. Aggarwal

Org. Lett. 2017, 19, 2762 (DOI: 10.1021/acs.orglett.7b01124)


Homologation of Boronic Esters with Lithiated Epoxides

Roly J. Armstrong and Varinder K. Aggarwal

Org. Synth. 2017, 94, 234 (DOI: 10.15227/orgsyn.094.0234)


Catalytic Enantioselective Synthesis of Atropisomeric Biaryls by a Cation-Directed O-Alkylation

John. D. Jolliffe, Roly. J. Armstrong and Martin. D. Smith

Nat. Chem. 2017, 9, 558 (DOI: 10.1038/nchem.2710)


Cation-Directed Enantioselective N-Functionalization of Pyrroles

Roly J. Armstrong, Melissa D’Ascenzio and Martin D. Smith

Synlett 2016, 27, 6 (DOI: 10.1055/s-0035-1560813)


Catalytic Enantioselective Synthesis of Atropisomeric Biaryls: A Cation Directed Nucleophilic Aromatic Substitution Reaction

Roly J. Armstrong and Martin D. Smith

Angew. Chem. Int. Ed. 2014, 53, 12822 (DOI: 10.1002/anie.201408205)


Furanyl Cyclic Amines: a Diastereoselective Synthesis of 2,6-Syn-Disubstituted Piperidines Under Thermodynamic Control

Matthew O’Brien, Andrew Leach, Roly J. Armstrong, Keting Chong and Ross Sheridan

Org. Biomol. Chem. 2012, 10, 2392 (DOI: 10.1039/C2OB07008A)