Late replicating CNVs as a source of new genes

The order in which DNA is copied during the cell division process reflects the evolutionary history of living beings: the oldest genes are copied first, and afterwards the genes that appeared later

The authors propose an original model that would explain how regions of the genome that are copied later on facilitate the birth of new genes with specific functions in tissues and organs

Press release of the work by David Juan et al (Biology Open 2013) carried out with Alfonso Valencia at CNIO.

Source: A CNIO study recreates the history of life through the genome | cnio.es

From happiness on Twitter to DNA organisation

Assortativity, a property used in network analysis, helps to identify the proteins that ensure the correct folding of DNA inside the nucleus

The new perspective allows the integration of different kinds of Big Data, unravelling the 3D configuration of the genome

Last year’s press release of the work by Vera Pancaldi et al (Genome Biology 2016) carried out with Alfonso Valencia at CNIO.

Source: From happiness on Twitter to DNA organisation | cnio.es