
We explore the frontiers of pain to benefit patients
Our work crosses the disciplines of neuroscience, pharmacy, psychology, and clinical research to better understand and treat pain.
Latest news
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Emma Beecroft invited to present In Naples, Italy at the 38th International AIGeDO Congress.
Emma Beecroft was invited to speak in Naples, Italy, at the 38th International AIGeDO Congress on 10th October 2025. One of the core mission statements of the Italian Association for Gnathology and Orofacial Pain (AIGeDO) is to enhance practitioner expertise and patient care in this specialized field, making Emma’s invitation to present alongside eminent international…
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British Orthodontic Society ASM
Justin was invited to present at this prestigious conference (16th Oct 2024) to discuss the management of TMD and the new guidelines available to help all healthcare professionals with TMD. He also explained some of the latest science behind changes in the mouth and face, pain pathways and central brain changes. His presentation can be…
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Team present work at World Endodontic Congress in Glasgow
The team were well represented, with Professor Justin Durham, Dr Jamie Coulter, and Dr David Edwards presenting their research at the World Endodontic Congress held in in Glasgow in Sept 2024. Click here to access materials from this conference
Current projects
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FacE-PD- Facial pain Experience in Parkinson’s Disease
This study aims to understand the types of pain affecting the face, head and mouth regions in people with Parkinson’s disease. Most people living with Parkinson’s disease experience pain, and this pain is often not well managed. Pain acts as the body’s warning system, signalling that something may be wrong so that the area can […]
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Mediators and moderators of change following attendance at a Pain Management Programme
This study proposed an updated cognitive-behavioural model of persistent pain. Predicted relationships between variables informed by the model will be tested using multiple regression analyses, advancing our understanding of how psychological factors can be successfully targeted to improve clinical management of persistent pain.
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Seeking treatment for painful TMD
The experience of jaw pain that lasts for more than a few months can be an uncertain experience both for patients and professionals. Management may fall between the roles of dentist or GP and many people are unclear about who to consult. Self-management is recommended as first-line treatment, possibly alongside other conservative options. In practice […]
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Investigating the role of the kynurenine pathway in irreversible pulpitis
The kynurenine pathway is responsible for the catabolism of the essential amino acid kynurenine. This pathway has been linked to acute and chronic pain in animal models of viral infections. Research by the team has shown upregulation of this pathway in pulpititis (toothache) and it appears to be pushing the pathway towards neuroinflammation and pain. […]
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OldPain2Go
A randomised pilot virtual feasibility study for a virtual randomized control trial of a novel brief intervention for people with low back pain.
Our work is funded by









