We explore the frontiers of pain to benefit patients
Our work crosses the disciplines of neuroscience, pharmacy, psychology, and clinical research to better understand and treat pain.
Latest news
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Emma Beecroft invited to present In Naples, Italy at the 38th International AIGeDO Congress.
Emma Beecroft was invited to speak in Naples, Italy, at the 38th International AIGeDO Congress on 10th October 2025. One of the core mission statements of the Italian Association for Gnathology and Orofacial Pain (AIGeDO) is to enhance practitioner expertise and patient care in this specialized field, making Emma’s invitation to present alongside eminent international…
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British Orthodontic Society ASM
Justin was invited to present at this prestigious conference (16th Oct 2024) to discuss the management of TMD and the new guidelines available to help all healthcare professionals with TMD. He also explained some of the latest science behind changes in the mouth and face, pain pathways and central brain changes. His presentation can be…
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Team present work at World Endodontic Congress in Glasgow
The team were well represented, with Professor Justin Durham, Dr Jamie Coulter, and Dr David Edwards presenting their research at the World Endodontic Congress held in in Glasgow in Sept 2024. Click here to access materials from this conference
Current projects
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Mediators and moderators of change following attendance at a Pain Management Programme
This study proposed an updated cognitive-behavioural model of persistent pain. Predicted relationships between variables informed by the model will be tested using multiple regression analyses, advancing our understanding of how psychological factors can be successfully targeted to improve clinical management of persistent pain.
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MiTiGate trial
MiTiGate Trial: Managing chronic Myalgia Temporomandibular Disorder: a pragmatic randomised controlled trial of Botulinum toxin type A, lidocaine, and amitriptyline/gabapentin, with internal pilot and cost-effectiveness analysis To learn more, visit the MiTiGate Trial website here: https://www.mitigatetrial.co.uk/ To self-refer to the trial, please email nuth.mitigate@nhs.net Plain English summary of the study Temporomandibular disorders (TMD) affect the […]
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Can we improve pain education using experiential methods?
The way that people understand pain is important. Typically, believing that pain is caused only by physical factors and using only passive modalities of treatment are both associated with a poorer prognosis. Unfortunately, this is exactly what many people do believe about pain including some health professionals! A recent project carried out by students from […]
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Investigating the role of the histamine system in chronic pain
Histamine, acting through all four types of histamine H1-H4 receptors, is arguably the most pleiotropic molecule in the human body. Since the cloning of H3R in 1999, there has been an increased interest within the pharmaceutical industry to discover and develop ligands to this receptor to target several diseases including neuropathic pain. However, while evidence […]
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Sarcopanc Study
Prospective longitudinal evaluation of Sarcopenia, health-related quality of life and correlation with blood and stool-based microbiome in moderately severe and severe acute pancreatitis.
Our work is funded by
