Opportunities to be involved in research
The following studies are actively recruiting participants:
Current projects
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EXTIRPATE study: Irreversible Pulpitis

Dental pain mechanisms remain poorly understood. Outcomes from current approaches to managing acute dental pain are suboptimal. EXTIRPATE focusses on developing a biological model to better understand peripheral and central pain mechanisms, explore the effect of current approaches on these mechanisms and investigate new treatment approaches.
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OldPain2Go
A randomised pilot virtual feasibility study for a virtual randomized control trial of a novel brief intervention for people with low back pain.
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Sarcopanc Study
Prospective longitudinal evaluation of Sarcopenia, health-related quality of life and correlation with blood and stool-based microbiome in moderately severe and severe acute pancreatitis.
Our Research Themes

Mechanisms and pathways of pain
Our work aims to understand how and why acute and persistent pain is experienced in painful conditions such as toothache, persistent facial pain, and neuropathic pain.
Pain therapeutics and clinical trials
In this research theme, our work explores new targets to treat painful conditions and assesses the efficacy, safety, and cost-effectiveness of clinical treatments.


Pain diagnostics
This work aims to improve on the current methods that clinicians have to diagnose pain conditions, and to measure and assess people’s experience of pain.
Applied pain research
Our research uses innovative clinical research, integrating multidisciplinary perspectives, to explore how best to help people who suffer from painful conditions.

Our Collaborators

Academic collaborators
- Osaka University, Japan
- University of Minnesota, MN, USA
- Aarhus University, Denmark
- University of Liverpool, UK
- University of Sheffield, UK
- University of Leeds, UK
- University of Manchester, UK
- Durham University, UK
Industrial collaborators
We work with several companies in the pharmaceutical and medical device sectors.
