Mitral valve development

From Bill Chaudhry and Deb Henderrson

Mr Francis Wells, the internationally recognised cardiac surgeon from Papworth Hospital Cambridge, and our longstanding colleague Professor Bob Anderson, are in the late stages of producing a book for Springer Nature Publishers about the degenerating mitral valve. The work is aimed at clinicians and provides a broad discussion of the mitral valve from a scientific perspective. It is especially timely as the  developmental basis of many degenerative conditions, for example mitral valve prolapse, are increasingly recognised. We are honoured to be involved and have written a chapter explaining the developmental molecular genetics that control mitral valve development. Our chapter is specifically written for the clinician, outlining important aspects, but not burdening with scientific jargon. It is of relevance to topics of our research including hypoplastic left heart syndrome, atrioventricular septal defects and bicuspid aortic valve. Developmental anatomy and surgical aspects are provided by Bob and Francis in other chapters, and a host of international experts are adding their expertise in clinical genetics and physiology. We will post publication details in due course.

What do patients with ACHD really think?

The physical and emotional long-term effects of having CHD are usually seen from the medical viewpoint. But increasingly we are aware that the clinic is not always aligned to what patients might actually want or feel. The ACHD team in Newcastle have joined the Approach IS II study lead by Philip Moons in Belgium. This international study will explore how patient-reported outcome measures (PROMs) and patient-reported experience measures (PREMs), differ between patients in different countries and also try to identify the healthcare needs of older adults with congenital heart disease, who may be quite frail. 

To find out more contact louise.coats@newcastle.ac.uk