Mitral valve development

From Bill Chaudhry and Deb Henderrson

Mr Francis Wells, the internationally recognised cardiac surgeon from Papworth Hospital Cambridge, and our longstanding colleague Professor Bob Anderson, are in the late stages of producing a book for Springer Nature Publishers about the degenerating mitral valve. The work is aimed at clinicians and provides a broad discussion of the mitral valve from a scientific perspective. It is especially timely as the  developmental basis of many degenerative conditions, for example mitral valve prolapse, are increasingly recognised. We are honoured to be involved and have written a chapter explaining the developmental molecular genetics that control mitral valve development. Our chapter is specifically written for the clinician, outlining important aspects, but not burdening with scientific jargon. It is of relevance to topics of our research including hypoplastic left heart syndrome, atrioventricular septal defects and bicuspid aortic valve. Developmental anatomy and surgical aspects are provided by Bob and Francis in other chapters, and a host of international experts are adding their expertise in clinical genetics and physiology. We will post publication details in due course.

Hello, Hello – Its Good to be Back!

from Newcastle University Congenital Heart Disease Group

The Faculty of Medical Sciences at Newcastle University was completely reorganised in 2019. We reduced our number of institutes from six to three: the BiosciencesTranslational and Clinical Research and Population Health Sciences Institutes.

As part of this restructuring the old research centres, including the Cardiovascular Research Centre, were dissolved. In their place are Themes that cut across all three Institutes and are focussed on the future direction of academic research in our University. 

We, congenital heart researchers, have taken the opportunity to make new connections with others in the Reproduction, Development and Child Health (RDCH) Theme. We remain closely linked, but distinct from our colleagues in the Vascular Biology and Medicine (VBM) Theme and some colleagues have joint affiliation. Congenital heart clinicians in Newcastle hospitals, who are active in research, are affiliated to the Congenital Heart Disease research group and the RDCH Theme. We are also part of a wider community through the North East and North Cumbria Congenital Heart Disease Network.

On these web pages, we will post information about our research, our meetings and list contact details about our members. Enquiries about congenital heart disease research should be directed to louise.coats@ncl.ac.uk or bill.chaudhry@ncl.ac.uk and we will try to connect you with the right people.