Opportunities to be involved in research
The following studies are actively recruiting participants:
Current projects
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MiTiGate trial

MiTiGate Trial: Managing chronic Myalgia Temporomandibular Disorder: a pragmatic randomised controlled trial of Botulinum toxin type A, lidocaine, and amitriptyline/gabapentin, with internal pilot and cost-effectiveness analysis To learn more, visit the MiTiGate Trial website here: https://www.mitigatetrial.co.uk/ To self-refer to the trial, please email nuth.mitigate@nhs.net Plain English summary of the study Temporomandibular disorders (TMD) affect the…
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Modulation of pain perception

Pain is a salient percept that can draw our attention away from our current task so we can deal with potential bodily harm. We are interested in how our thoughts and actions can help us deal with pain, for example by distracting us from a painful stimulus. To address this, we use different tasks to…
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Mediators and moderators of change following attendance at a Pain Management Programme
This study proposed an updated cognitive-behavioural model of persistent pain. Predicted relationships between variables informed by the model will be tested using multiple regression analyses, advancing our understanding of how psychological factors can be successfully targeted to improve clinical management of persistent pain.
Our Research Themes

Mechanisms and pathways of pain
Our work aims to understand how and why acute and persistent pain is experienced in painful conditions such as toothache, persistent facial pain, and neuropathic pain.
Pain therapeutics and clinical trials
In this research theme, our work explores new targets to treat painful conditions and assesses the efficacy, safety, and cost-effectiveness of clinical treatments.


Pain diagnostics
This work aims to improve on the current methods that clinicians have to diagnose pain conditions, and to measure and assess people’s experience of pain.
Applied pain research
Our research uses innovative clinical research, integrating multidisciplinary perspectives, to explore how best to help people who suffer from painful conditions.

Our Collaborators

Academic collaborators
- Osaka University, Japan
- University of Minnesota, MN, USA
- Aarhus University, Denmark
- University of Liverpool, UK
- University of Sheffield, UK
- University of Leeds, UK
- University of Manchester, UK
- Durham University, UK
Industrial collaborators
We work with several companies in the pharmaceutical and medical device sectors.
