Category Archives: Musculoskeletal news

We’re at the Edinburgh Science Festival this weekend

Our Black Box project (https://blogs.ncl.ac.uk/blackbox/) will be featured at the Edinburgh Science Festival on Saturday the 9th of April and will screen until the 9th of June. Come say hi if you’re in Edinburgh this weekend, we will be hosting an opening talk at 2pm.

The full program of our Edinburgh show can be found here: https://www.sciencefestival.co.uk/mediaLibrary/other/english/58530.pdf

Black Box a guest feature at the Edinburgh Festival of Science next month

Black Box https://blogs.ncl.ac.uk/blackbox/ is a pop up cinema project that explores life, kinship, identity and futures through the medium of film. Developed in 2019 by an artist (Louise Mackenzie) and a scientist (Kasia Piróg), it is a great pleasure to be able to show it at the Edinburgh Science Festival next month

https://www.sciencefestival.co.uk/event-details/black-box-artist-talk

A lovely lab day out in Corbridge

Being a scientist is not only about the work, results and publications, but also about forging links and networks, and long lasting friendships that can help in these discoveries in the future. We had a lovely day out in Corbridge yesterday with our students and joint with the Briggs lab. Spring is definitely here!

Black Box is coming back!

Our Black Box cinema project will be visiting the Summerhall Exhibition as part of the Edinburgh Science Festival in April this year!

Opening the door on the inner workings of scientific research, BLACK BOX is a curatorial pop-up cinema project, founded by artist, Louise Mackenzie and scientist, Kasia Pirog. Curating film inspired by and expanding upon scientific themes, BLACK BOX showcases works by artists and researchers involved in a creative and critical engagement with science. For Edinburgh Science Festival 2022, BLACK BOX presents KINSHIP – a programme of short films that reflect upon the many evolving relationships that begin with the body. Who or what connects us, who is host and who is guest?

BLACK BOX is supported by the Cultural Negotiation of Science, Northumbria University and the Biosciences Institute, Newcastle University.

We are very excited, please watch this space for more details. Meanwhile, if you’d like to know more about the Black Box project, please click here: https://blogs.ncl.ac.uk/blackbox/

Exercise and osteoarthritis

We have a new blog post!

With the help of our Dunhill Medical Trust Project Working Group we have looked into the benefits of exercise and discussed the different types of exercise that can be beneficial for the management of osteoarthritis. We have also identified several helpful resources by Versus Arhtritis and the NHS and listed them all here: https://blogs.ncl.ac.uk/katarzynapirog/osteoarthritis-and-exercise/

Please get in touch if you’d like to know more.

The final programme of the BSMB meeting next week is here!

6th SEPTEMBER 2021

12:30-12:45 – Registration

12.45-1.00 OPENING – Kasia Piróg (Newcastle University, UK) – Welcome and Introduction to the platform

1.00-2.40 RARE DISEASES OF CONNECTIVE TISSUES (chaired by Kasia Piróg and Blandine Poulet)

1.00-1.35 Inês Alves (ANDO, Portugal) – The matrix for research collaborations – The patient expertise in rare disease

1.35-1.50 Brendan Norman (University of Liverpool, UK) – Altered bone metabolism in the rare inherited disease alkaptonuria

1.50-2.05 Eleanor Feneck (King’s College London, UK) – A functional deficit in connective tissue fibroblasts contribute to the cellular and molecular disease pathology in Radial Dysplasia

2.05-2.40Matthew Warman (Harvard University, USA) – What we’ve been doing during the pandemic: studying serotonin effects on bone, removing lubricin domains using iGONAD, and evaluating the effect of killing articular chondrocytes in newborn mice

2.40-4.00 TEA AND COFFEE Posters + AGM

4.00-5.40 RARE DISEASES OF CONNECTIVE TISSUES II (chaired by Kim Midwood and Peter Bell)

4.00-4.35 Brendan Lee (Baylor College of Medicine, USA) – Insights into matrix alterations in tendon homeostasis and repair by studying Osteogenesis Imperfecta

4.35-4.50 Jessica Llewellyn (University of Pennsylvania, USA) – EFEMP1 affects structure and function of the extrahepatic bile duct

4.50-5.05 Helen Dietmar (Newcastle University, UK) – Matrix metalloproteinase 9 –a potential biomarker for COMPopathies

5.05-5.40 Francesco Ramirez (Mount Sinai, USA) – Why Marfan syndrome’s patients are disproportionally taller?

5.40-5.55 Kim Midwood – John Couchman: Vote of thanks

6.00-7.00 ONLINE SOCIAL

7TH SEPTEMBER 2021

10.00-12.40 RARE DISEASE MECHANISMS (chaired by David Wilkinson and Francesca de Sousa Brito)

10.00-10.35 Laurence Legeai-Mallet (INSERM) – New therapeutic approaches for achondroplasia

10:30-11.00 TEA AND COFFEE (Posters)

11.00-11.35 Su Lwin (King’s College London, UK) – Emerging therapies for epidermolysis bullosa

11:35-11.50 Emily Shorter (University of Liverpool. UK) – A Systematic Meta-Analysis and Multi-Source Information Network Identify Novel Osteoarthritis-Associated Genes

11.50-12.05 Franziska Lausecker (University of Manchester, UK) – Identification of an altered matrix signature in kidney ageing and disease

12.05-12:40 Alison Gartland (Sheffield University, UK) – Primary Bone Cancer from Dinosaurs to Dogs

12.40 –1.15 Lunch break

1.15-2.15 BSMB EARLY CAREER RESEARCHER AWARD (chaired by James Whiteford)

2.15-3.55 DRUG REPURPOSING AND PATIENT PERSPECTIVE (chaired by James Whiteford and Emily Shorter)

2.15-2.50 Rachel Lennon (University of Manchester, UK) – Kidneys, basement membranes and Alport syndrome

2.50-3.05 Tonia Vincent (Oxford University, UK) – Musculoskeletal manifestations of Marfan Syndrome including long bone length and kyphosis are rescued by losartan treatment during adolescent growth in mice

3.05-3.20 Juliette Hughes (University of Liverpool, UK) – Distribution of ochronotic pigment in the connective tissues of an alkaptonuria cadaver

3.20-3.55 James Gallagher (University of Liverpool, UK) – What we learned about the ECM whilst developing a therapy for the rare genetic disease AKU

4.00-4.15 PRESENTATION OF PRIZES & CLOSE OF MEETING (chaired by Andrew Pitsillides, Kim Midwood and Kasia Piróg)