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The brain continuously adapts and learns to respond to ever-changing behavioural demands. It achieves thisby modulating the function of nerve cells or neurons, and their networks through the release of neuromodulators. Neuromodulators, such as acetylcholine, serotonin or dopamine, are chemical messengers that govern the emergence of brain oscillations by controlling the activity of neural networks and regulate shifts between behavioural states such as sleep and wakefulness or distraction and attention. My research seeks to understand the mechanisms through which neuromodulators operate and utilize this knowledge to build computational models of how the brain implements learning.