Category Archives: Musculoskeletal news

Congratulations Dr Beth Gibson!

Beth defended her PhD thesis on investigation of the pathomolecular mechanism of two aggrecan mutations leading to OCD and SEMD using mouse models of disease.

Thank you to Prof Frank Zaucke from Frankfurt and Dr Andy Knight from Newcastle University for examining the thesis and well done Beth, all the best in your future career!

 

4th October 2018 – Dame Allan’s Schools biennial Higher Education & Careers Convention

Dame Allan’s Schools holds a biennial Higher Education & Careers Convention and invire presenters, employers, and universities to inspire and inform their students as they make plans for their future. We’ll be there on the 4th of October, chatting about genetic research and academic life and inspiring the young minds. We’ll show some cool science too!

Interesting paper identifying human skeletal stem was published in Cell journal this month

Identification of the Human Skeletal Stem Cell

Charles K.F. Chan, Gunsagar S. Gulati, Rahul Sinha, Justin Vincent Tompkins, Michael Lopez, Ava C. Carter, Ryan C. Ransom, Andreas Reinisch, Taylor Wearda, Matthew Murphy, Rachel E. Brewer, Lauren S. Koepke, Owen Marecic, Anoop Manjunath, Eun Young Seo, Tripp Leavitt, Wan-Jin Lu, Allison Nguyen, Stephanie D. Conley, Ankit Salhotra, Thomas H. Ambrosi, Mimi R. Borrelli, Taylor Siebel, Karen Chan, Katharina Schallmoser, Jun Seita, Debashis Sahoo, Henry Goodnough, Julius Bishop, Michael Gardner, Ravindra Majeti, Derrick C. Wan, Stuart Goodman, Irving L. Weissman, Howard Y. Chang, Michael T. Longaker

Cell 2018; 175 (1), 43-56.e21 DOI: 10.1016/j.cell.2018.07.029

Our research at the Great Exhibition of the North

On Saturday the 28th of July we were presenting our bench to bedside research at the Great North Museum Hancock as part of the Great Exhibition of the North, an event celebrating innovation and excellence of science and technology in the North East. We chatted to approximately 100 people of all ages, presented out work and specimens and answered many interesting questions. Thank you all for visiting and making it a really enjoyable day!

If you missed us and would like to come see us another time, we’ll be present at Dame Allan’s Schools careers fair in October or keep an eye out for advertisements of our flagship Genetics Matters event, coming up end of February as part of the International Rare Disease Day!

Newcastle’s Skeletal Research Group at the MRC Festival of Medical Research

IGM and ICM scientists involved in the MRC funded CIMA (Centre for Integrated research into Musculoskeletal Ageing) project have organised an informative public engagement afternoon on Wednesday the 20th of June 2018 to chat to the members of the public about joints in health and disease, joint diseases and the impact of diet and exercise on joints’ health. The attendance is FREE, full programme attached below:

Our lab wins a technology prize in the 2017/18 BeHEARD competition!

The BeHEARD (Helping Empower and Accelerate Research Discoveries) Challenge is hosted annually by the Rare Genomics Institute and is open globally to researchers, foundations, or anyone whose research is constrained due to limited resources. It provides technology and financial grants for rare disease research. Families with a child afflicted with a rare disease have the opportunity to work with a network of academic researchers to develop research proposals tailored to advancing treatments for their child’s disease.

We just heard that our group won the technology prize in the 2017/18 competition. The prize is a vector constructed by Cyagen (worth $8,950) which will be used to generate a conditional knock-out mouse model that will greatly enhance our sudies of skeletal dysplasias. We are very grateful for this prize and we’re looking forward to the exciting project ahead!

Thank you to Prof Danny Chan and the Chan lab for hosting Beth in Hong Kong!

Beth Gibson (our PhD student) is back from her RUBICON secondment in Hong Kong. Beth had a successful and productive secondment analysing the spinal phenotype of two mouse models of aggrecanopathies, and particiapted in several meetings and conferecnces including the Little People of Hong Kong society. We would like to thank  Danny and his lab for hosting Beth and look forward to future collaboration.