


Ella, Felcitiy and Izzy busy making important contributions to science.
10/03/2025



Ella, Felcitiy and Izzy busy making important contributions to science.
10/03/2025
We have a 4 year fully funded PhD studentship available in the lab, in collaboration with Clare Mahon at Durham. Deadline 31st March at midday. See link for how to apply etc.
A chemical biology project investigating the recognition of glycans by lectins, important in many biological processes including bacterial infection, aiming to to make better lectin diagnostics.
Particularly suitable for anyone with a background in chemical biology, peptide synthesis or glycans.
28/02/2025
Izzy officially starts her 4th year MChem lab project with us today. Before Christmas, Izzy planned her project and undertook some skills training and will be working on her project to synthesise glycosylated amino acids until May. Welcome to the lab Izzy!
27/01/2025

It’s that time of year again and we had our 3rd annual Chemical Biology Christmas Symposium with the Kawamura group. We had a packed schedule of talks, interspersed with secret santa, a chirstmas quiz and a brand new smash hit game – “Will it sink or will it float”. All organised again this year by Emma, Tim and Tom from Akane’s group.






Above: Talks, quiz and secret santa. Below: Will it sink, or will it float?





13/12/2024
Written by MoSMed PhD student Ella Sames

Last Autumn, I started tutoring with The Brilliant Club Charity and undertook a placement teaching KS5 students at a local Newcastle School. This placement involved designing and delivering a seven-lesson course, based on my PhD research, with the aim of teaching students the skills to help them thrive at university. Whilst at secondary school, I was a pupil with The Brilliant Club, so I am aware of the positive impact this program can have on raising aspirations.
The goal of this charity is to instil confidence in young people from more disadvantaged backgrounds and encourage them to apply to highly competitive universities. In particular, this program targets students eligible for pupil premium or with parents who haven’t attended university, as there is evidence that meeting these criteria puts pupils more at risk of underachievement nationally.
For this placement I designed a course entitled ‘Decoding DNA: What are the Secrets of Your Genetic Code?’ The idea was to provide students with an overview of some key themes in molecular biology, such as DNA structure and function, the genetic code and X-ray crystallography. The teaching took place in small groups which gave students the opportunity to ask questions and work through problems collaboratively with their peers. It was rewarding to see students engage with the course and express an interest in studying natural sciences at university as a result of the program.
Teaching the course involved giving mini lectures on key concepts, reading through scientific sources and preparing hands on consolidation activities. Students particularly enjoyed the ‘pipe cleaner enzyme activity’ which involved using different coloured pipe cleaners to model the different orders of protein structure.
Overall, my experience as a tutor with The Brilliant Club was extremely fulfilling and a great way to encourage young people to pursue science in higher education
Nov 2024
Georgi gave a presentation at our Chemical Biology and Organic Chemistry seminar series within the department. The title was: “Investigating the substrate specificity of the GalNAc transferase ppGalNAcT1”
25/09/2025
The whole lab (Becca, Ella, Felicity, Georgi and Tom) spent the morning at Matfen GoApe! We had a great time, but didn’t get any photos as phones in pockets are not advised with a harness. Luckily we did get a certificate, so we can prove we did actually go!

30/08/2024
We’re very pleased to welcome Becca back to the lab to carry out a project over the next few weeks.
22/07/2024
We were celebrating in July as our former MChem student Becca collected her MChem in Medicinal Chemistry and PDRA Felicity got to collect her PhD degree (obtained under the supervision of Mike Hall, Julian Knight and Hanno Kossen at Newcastle). Congratulations to both of you on your achievements and surviving the degree ceremony on the hottest day of the year!

19/07/2024

We held our first Chemical Biology lab away day with the Kawamura group in Durham at the beginning of June. Supported by Newcastle University SAgE Faculty’s People Fund, 20 members of the lab comprising students, research associates, technical staff and the PIs spent a morning Dragon-boating on the river Wear, developing our teamwork to drive the boat along. (It was all going well until we got a bit out of sync and nearly capsized; how we didn’t all end up in the river is still a mystery to everyone!)





After some lunch on dry land, we then had an afternoon of skills training; a master class in curve fitting from Akane and making attractive presentations by Tim. Tom also organised some small group acivities around team work and communication; building the tallest spaghetti tower that could support a marshmallow (2 out of 5 were standing at the end!) and reproducing a lego model without being able to see it.





Overall it was a great day and made a measurable improvement to promoting the positive research culture we strive for within the group. A survey of team members conducted before and after the day out, revealed a significant increase in the scores reported for collaboration and collegiality, and how well people felt they knew the rest of the group.
Away days like this one help foster a healthy and positive work environment, and enhance team-based skills, which are essential for achieving collective success. We are very grateful for the financial support from Newcastle University SAgE Faculty’s People Fund for this activity.
07/06/2024