Change is the new normal: some ins and outs & exciting new projects

Working under the pandemic has not been boring. Everyone in the group is working ridiculously hard, some people are leaving and new people are arriving, and we have gained a variety of exciting new projects, which is a remarkable success under such trying conditions. Unfortunately, Rui Xin returned home to China to finish her PhD, while Dr Vincenzo Padricello has joined Eχponent® to perform work closer to his PhD interests. However, Dr Pani Adamou recently returned to the group to work on our expanding wastewater-based epidemiology (WBE) and NERC UK-India projects.

Relative to WBE, we were just awarded a research project by the Joint Biosecurity Centre called “Wastewater-based epidemiology for Her Majesty’s Correctional Service,” which will assess the value of WBE as an early warning of health conditions in contained facilities. The novelty with this work is that we are expanding wastewater analysis to include enteric bacterial pathogens, virus beyond SARS-CoV-2, AMR, and microbiomes. The work aims to assess the amenability of other infectious disease markers to WBE approaches. 

We also were recently awarded a new project by the Rising Tide Foundation called “Identifying Best Practice for Empowerment Through Entrepreneurial Freedom: A project for the marginalised in slum areas in Delhi, India.” This is an exciting multidisciplinary project led by Prof Pauline Dixon, studying social and technical approaches to improve the quality of life in several slum types in India. Dr Myra Giesen will move to this project on 1 April 2021 when it starts, and Dr Kelly Jobling will move part-time to the project later in the year when demands from her WBE work declines. 

Beyond the above work, we now have two Civil Engineering MEng students, Savannah Lawrence and Matt Day, performing their dissertation work on WBE data from DEFRA and JBC, while Katie Robins, PhD student, has just taken a part-time internship at DEFRA to work with their Senior Epidemiologist on merging environmental and human health data to enhance in health surveillance. Finally, we were just awarded a WIRe CDT PhD studentship, which will study “The future of wastewater-based epidemiology.” This is sponsored by the EPSRC, Northumbrian Water, and Scottish Water, and David and Dr Vanessa Speight at the University of Sheffield will supervise the studentship. An announcement will be made soon seeking applications. 

Although we are under lockdown, things are terribly busy here. I want to especially flag the heroic work by Marcos Quintela-Baluja and Kelly Jobling who are holding things together under these strange times. 

Pani is now a Senior Scientist at Cignpost Dignostics

More great news about Pani; she’s been hired as a Senior Scientist at Cignpost Dignostics (CD) to screen samples for Sars-CoV-2. CD provides this service to companies where social distancing measures are either impractical or unproductive, helping employers to create a safe working zone through testing. CD test samples on site, either in fixed or mobile lab units, providing accurate results within 2 hours using rapid health diagnostics. They test approximately 200 samples per day. Pani makes sure PCR results are accurate and meet standards, deals with any issues arising during the process, and delivers results on time. This is a great new experience for Pani; we are pleased to report she is happy being involved in a project related to COVID-19 screening in industry.

Coverage of our Covid-19 sewage surveillance work

Our involvement in the UK nationwide surveillance programme is highlighted in a news clip on MSNBC’s The 11th Hour with Brian Williams (15 July 2020) and in a Feature article in BJM, Sewage monitoring is the UK’s next defence against covid-19, by Chris Baraniuk (15 July 2020). Additionally, our UK work is reported in Con apoyo del CONACYT investigadores crearán herramienta que ayudará a controlar la pandemia en Paraguay from the Consejo National de Cienci y Technologia (13 July 2020). This describes the development of a national sewage SARS-CoV-2 surveillance program for Paraguay.

Nationwide programme for detecting COVID-19 in wastewater

We are one of the teams on the new £1m research programme seeking to establish an early warning of future outbreaks and reduce reliance on costly testing of large populations. The research programme led by the UK Centre for Ecology & Hydrology (UKCEH), also involves researchers from the universities of Bangor, Bath, Edinburgh, Cranfield, Lancaster, Oxford and Sheffield, plus the London School of Hygiene and Tropical Medicine. Read the news releases from Newcastle University and UKCEH. This work is an extension to our UK and Spanish SARS-CoV-2 Project.

Also see: 

  • BBC | News | Science & Environment Coronavirus: Testing sewage an ‘easy win’ – nice article, but we did not develop the original method for SARS-CoV-2. We have improved on the previous method to make it more exact and make it more possible to approximate the human population from which it came. 
  • BBC | World Service | listen from 17:56
  • BBC | Radio Newcastle | listen from 3:46:13

Monitoring Sewage for SARS-CoV-2, the COVID-19 virus

Engineering and Physical Sciences Council (EPSRC) funds have been provided to sample and analyse sewage to estimate local concentrations of SARS-CoV-2 (the COVID-19 virus) across networks in Spain and North East England. The aim is to develop a way to quantify the prevalence of the COVID-19 infected individuals across the regions based on sewage data. If successful, this monitoring would help public health officials identify possible infection ‘hot spots,’ which captures both symptomatic and asymptomatic individuals across a community.

The project is being co-led by Professor David Graham and Dr Marcos Quintela, with their close colleague Professor Jesús Romalde in Santiago. They also will be working with water industry partners Northumbrian Water and Labaqua, which is part of the SUEZ corporation.