My Internship at Organon

by Grace Preston, Stage 3 Biomedical Sciences

A Little Context

Hello, I’m Grace, I study Biomedical Science and I had the option to take a placement year away from studying and get into the job role behind my subject. I was one of the lucky few to be offered a year at Organon.  

Most of you will not have heard of Organon but once I did my research into the company and its values, I found it to be the perfect option for me.  

Organon is a global women’s healthcare company based in 62 countries (to be precise) but lucky for me I was based just around the corner in Cramlington. Different sites vary in testing and research but in Cramlington we focus on testing drugs already on the market (known as stability) and new drugs preparing to be put on the market (known as release). 

Me preparing standards.

A Day in the Life of a Lab Intern

After our training we were given the teams we would be based in. I got put into the montelukast team also known as singular (I know, long drug name) which is a drug for asthma specifically for children’s asthma attacks but can be used for lots more. The team were so helpful in getting me up to speed with the number of drugs we receive each week and the typical plan for the week to make sure we release them before their guideline date. I soon learnt each week is different with which type of drug we received and trust me I still can’t name you every single variation of each different drug and how many different tests are needed for them.

My days varied with the different training I received during my year such as UV work, use of DR baths, content uniformity and assays all used to determine how effective the drug is through time points. After a couple months our teams changed and become merged with another drug called Zocor also known as Simvastatin which is for lowering cholesterol.  

Me using a high-performance liquid chromatography (HPLC) system.

Is It Challenging?

Of course it is, as is every job. Going from a full-time uni student going out with friends (a little too much I care to admit) and basing your life around lectures and which test or essay is next to a full time 9-5 job is a struggle at first, but you’ll be surprised to know how easy it becomes after a few weeks. The timelines and responsibility were very similar to university, but the stress is so much different at the end of the day you finish work and that’s your day done; not “oh no I need to revise”.  

My Advice

If you’re looking for placements look into the companies and job roles so you can understand the expectation and if it suits you. Theres no harm in applying for lots and when you get to the interview stage, practice your questions and even make some of your own for when you get there, and do some research into the company but most importantly just be yourself.

Ps LinkedIn is amazing for connecting with current placement students as well as current placements on offer. 

Motivation (via Giphy)

So Should You Do a Placement…?

Simple answer, absolutely! The experience in a scientific working atmosphere is amazing. It helps you gain experience for your future jobs as well as lets you understand your subject so much better and helps you realise what areas you’d like to be based in in later life. I have not only gained so much experience scientifically but also made some incredible friends and gained so much more working life skills that I will 100% be using.

It may be stressful looking at jobs in areas you’ve never even looked at before but trust me just do it, everyone is so welcoming and helpful and you’ll be surprised how much you can learn in just a year. 

So, take this as a sign to start placement hunting and get your CVs and cover letters sent in, you won’t regret it! 

An Insight Into Clinical Operations at Roche

by Rebecca Watson, Stage 3 Physiological Sciences

I spent my 13-month industrial placement at Roche Products Ltd., Welwyn Garden City. My role was in Global Clinical Operations as a Clinical Operations Lead (COL) based in the Product Development department. Initially, I did not know what to expect going into this huge industry to do a job that I had no expertise in but I quickly got to grips with the responsibilities of my role and began to learn more about the pharmaceutical industry.  

Roche Products Ltd

Roche is a global healthcare company, with branches in both pharmaceuticals and diagnostics, and innovative solutions across a range of different therapeutic areas. Since being founded in 1896, Roche has created a number of pharmaceutical and diagnostic solutions to help diagnose and treat a number of life threatening diseases, one such solution being Kadcyla used in the treatment of HER-2 positive breast cancer.  

The Roche Welwyn Garden City office.

Day to Day

At the beginning of my placement I was assigned to a clinical trial and began to get to know my study team, starting with regular team catch ups and having 1-1s with the members of the team to find out more about what their responsibilities were on the study and how I could help with their tasks. This helped me develop my understanding of the fundamentals of a clinical trial and gain an appreciation for the importance of Operations in ensuring the smooth running of the trial.  

Eventually I progressed to managing my own projects on the study, such as creating a weekly information bulletin for the clinics where the trial was ongoing, collating important recruitment and data information from the study systems and presenting it in an easily digestible format, highlighting the most relevant updates for the busy sites to remain informed on the progress of the trial. This had a hugely positive impact on my attention to detail and gave me the opportunity to get to grips with the study systems to get the information that I needed to create these before moving on to bigger tasks.  

Around halfway through my placement, I was given the responsibility of having oversight of the trial in 5 of the countries that we had active on the study. This was a task I had been eager to get experience in since joining the study team and proved to be a large step up, having to relay study level updates to the country COLs to keep them informed of any upcoming changes. This also involved preparing for meetings in advance, collecting any updates from team calls, data metrics reports and recruitment figures to get the most out of these meetings. Although this was challenging at times, it really helped me develop my ability to be comfortable in asking questions as I was the one responsible for finding answers. Overall this was one of my biggest achievements throughout the whole of my placement (not to mention never missing one of my 7am calls). 

The Roche Products Ltd. Welwyn Garden City office Christmas party 2023. Pictured left to right: Rebecca Watson, Paayal Shah, Jude Abou Chakra, Mehreen Haque, Jessica Patrick, Jessica Williams.

Later on in my placement, I began to get involved in work outside of Clinical Operations in Product Development, taking the opportunity to work with colleagues in Pharma Biosamples Solutions (PBS) to gain experience in the long term storage of patient samples. This was a great experience and it was a privilege to get to know the team there, who were always willing to help with any tricky requests that I received.  

The Office Community

Aside from study work on my placement, I was also very involved in the office community at Welwyn, having co-created the Roche Badminton Club with another placement student. We ran a session every Tuesday evening at a local sports hall which was open to players of all abilities across all departments. This was very well attended amongst our early in careers colleagues and even attracted some seasoned players who had been at Roche for a number of years. This was a great way to increase our visibility in the community and led to us making some valuable connections with colleagues in other departments. 

Celebrating a point at one of our Tuesday evening badminton sessions. Pictured left to right: Riyana Raja, Grace Tucker, Jude Abou Chakra.

I also enjoyed being part of the Eco-Garden committee and participating in events such as the Family and Friends Day where we ran a craft stall for colleagues and their children to decorate small garden ornaments that were then hung up in the garden. We even managed to grow a few crops over the year which were available for anyone in the office to help themselves to.  

The Eco-Garden committee and our craft stall at the Family and Friends Event 2023. Pictured left to right: Grace Tucker, Saad Bin Huda, Rebecca Watson.

A Few Final Words

To anyone contemplating doing a placement, I would 100% recommend it as it has given me not only a greater understanding of this role and industry, but also a greater appreciation for my own abilities and vastly improved my confidence for going forward into my career after university. Good luck on your applications and make the most of the year! 

The wonderful world of Microbiology

Ever wondered what goes on in the Newcastle University Biomedical Sciences labs behind the scenes? On Wednesday 28th February, researchers from the school of Biosciences, Nutritional and Sports Sciences organised a Microbiology research fair to give students a sneak peak into the fascinating world of microbiology research, PhDs, careers, summer placements and final year projects. There were also amazing opportunities to go and see the research laboratories and facilities on the lab tours. So I couldn’t resist tagging along to see what was going on – and let me tell you, it didn’t disappoint! From chatting with researchers deep in ground-breaking projects to getting a first hand look at cutting-edge equipment, there was so much to discover.

Students were talked through different research at each station

There were many areas of research, but one big topic that caught my attention was the gut microbiome. Even though this research fair was mainly aimed at Biosciences students, it was interesting as a student dietitian myself to see the vast amount of research that the University is conducting on this area, as it is a really new and exciting area in the advancing field of nutrition. Some PhD students were researching into how fibre is broken down in the gut by different strains of gut bacteria and how the body uses these chemicals that are produced. One student was focussing particularly on how caramelised sugars are digested by the gut microbiome, and even though excess sugars are seen to have harmful effects on health, some gut bacteria can break these down to useful chemicals!

One of the most interesting stations for me was the station that was showing a machine taking species from the sea to make antibiotics. A remote machine goes down 4000m deep in the South Pacific and takes samples from the bottom of the ocean. It was fascinating how intricate the collection process was, yet how simply the machine could extract the sediment. These samples are then transported back to the labs and the microbes are cultured. The microbes of particular interest to them are Actinomycetes, and these produce 70% of all antibiotics. These actinomycetes have the ability to kill MRSA and other large strains of microbes. These researchers really had a passion for the undiscovered potential of the sea, and it seems like this is a really up and coming area of research.

Here you can see the machine arm working at the bottom of the sea floor to extract the sediment

The most exciting part of the afternoon was the tours of the research labs! From state-of-the-art equipment to cutting-edge facilities, the students got a first hand look at what goes on in the world of research. Our tour leader’s research was focussing on Staphylococcus Aureus. Yes, we are talking about the superbug MRSA – a bacteria that is very complicated as it has the potential to cause lots of different diseases.

Gel electrophoresis equipment in the laboratory
Our fab laboratory tour guide showing us her MRSA superbug cultures

The labs had loads of cool equipment – the second one we were showed around was a biochemistry lab with research focussing on proteins. Their mission is to purify tiny proteins to find the protein of interest, and then grow crystals of it. The coolest machine in the lab by far was the X ray generator, which focuses on the protein crystal. The x ray signal is then amplified and detracts using electron density, which will rotate and shoot as many x rays as possible to collect the data. This helps them to calculate the structure of the molecule with the help of computer software, therefore figuring out what the protein looks like and its function. Ever heard of the lock and key interaction? Well, imagine the protein as the lock and the target molecule as the key. With 3D printing technology, these researchers can create super cool models of the protein structure. And here’s a fun fact to wrap things up – this model below was created of a tyrosine residue. Turns out, it’s not just some fancy scientific term – it’s actually a super important ingredient that can be used in toothpaste to break down plaque in your mouth, showing how important this science research is in everyday life!

The 3D model of tyrosine residues generated by the 3D printer


Biomedical scientists are also actively involved at the Freeman Hospital in researching urinary tract infections (UTIs) through a patient-centred approach, involving collaboration with clinicians ant their patients. This approach emphasizes the importance of understanding the individual needs and experiences of patients in managing and treating UTIs. By working closely with clinicians and patients, these biomedical scientists are contributing to the development of personalized treatment strategies and interventions to improve patients outcomes. They also are conducting laboratory based research to better understand the underlying causes of UTIs, including identification of pathogens, antibiotic resistance patterns and host immune responses to help advance our understanding of them and develop more effective treatment options. This work shows the diverse scope of the Biomedical science profession, which extends beyond traditional lab-based research to the hospitals to use more patient-centred approaches to better improve quality of care.

Judith and Phillip are both active researchers within the Freeman Hospital and with Newcastle University

The research showcased at the fair provided a glimpse into the groundbreaking research happenign at the university in various fields. From the gut microbiome to exploring the potential of the sea for antibiotic discovery, students had so much opportunity to ask questions. The future of science is definitely looking bright!

My placement year at Reckitt

By Joel Tyler

Reckitt is a Fast Moving Consumer Goods (FMCG) company with offices and employees spread out across the world. Founded in 1870, Reckitt started off by selling laundry starch in Hull, now, Reckitt operates in a range of markets and is the owner of various health and medicinal brands such as; Nurofen, Strepsils, Dettol, Vanish and Durex to name a few. 

Some examples of Reckitt products sold around the world. Via Google Images

My placement year was a lab-based role involved in working for the brand Veet, this included both formulation manufacturing and analytical testing for the depilatory cream products currently available to buy in shops as well as a new product being developed and to be released in the near future. 

A day in the life

Due to the fast paced environment (as an FMCG company), I found that there was always something to do all the time and the days/weeks were fairly similar. This is because of the constant manufacturing of different formulations of new products to be tested under different stability conditions, and then followed by analytical testing of the formulations to identify which was the best product.  

Using a light microscope to examine the structure of a hair sample

Therefore, my normal day would start with a team meeting to discuss where everyone was at with formulation/testing work and to discuss steps/processes going forward or if anything had failed/gone wrong with the batch. After, I would go to the lab to complete any formulation/analytical testing which needed to be done.  

I enjoyed this working routine as it meant I gained far more lab experienced than I initially thought I would, it was always very clear what work I needed to be doing and I was always given lots of support if things ever went wrong. I would say I definitely wasn’t treated as a ‘student’ but a very integral part of the team which also surprised me! 

Student Project

In the second half of my placement, I organised and created a project alongside my line manager which involved testing the tensile strength of hair using a texture analyser and a brand new test method. I also presented my results to the rest of the Veet brand to explain my findings. 

During my project I had to test thousands of individual hair samples and as a result became the most experienced within the lab at using the texture analyser, this meant that I had the opportunity to present and perform samples to higher up executives within the company (and even the Global Head of R&D) which was an amazing experience. 

Hair sample being tested in the Texture analyser to investigate the tensile
A Becomix machine used to formulate and manufacture different depilatory creams. Via Google Images

Why I chose to do a placement

I decided during first year of my degree that I wanted to do a placement, specifically a lab based placement, because I was enjoying being in the lab at university but I was curious if I would enjoy working in a lab as a full time job to give myself an idea for post graduate jobs.  

Having completed my full year, I now know I could happily work in a lab after university, so applying for lab based roles isn’t a big risk but also that I know I can work efficiently and thrive under the environment. My placement gave me many challenges along the way (which is natural when learning new things in a short space of time) but I gained valuable and employable experience in overcoming these obstacles and realised that I feel confident within a lab setting.

I would highly recommend doing a placement!

Completing my placement year was definitely one of the most important things I have done within my life. The obvious reasons being all the different skills and attributes which I learnt/developed along the way, but also, the experiences which are available in just one year really surprised me, with the huge amounts of social networking needed to be done for my day to day job, I found myself naturally speaking to and shadowing other departments, creating professional relationships which will last for life. So I would say even if you are even considering to apply for placements, just go for it because you won’t regret it! 

A year at Pharmaron UK

By Billy James

Most, if not all of you, will have never heard of Pharmaron. Neither had I, till I applied for a placement in their Formulation Development Team. 

A little context 

I first came across Pharmaron when looking for placements back in September 2021. A lecture entitled “Drug Formulation” had sparked my interest in the first few weeks of term, so when I came across Pharmaron’s “Formulation Development” placement I applied straight away.

 In preparation for interviews I did a little research into the company and found out they were a CDMO, or contract development and manufacturing organisation. Essentially, Pharmaron take on client contracts for anything ranging from drug discovery all the way through to manufacturing drug product for clinical trials.

Two of the buildings at Pharmaron’s Hoddesdon Site

My Placement

The placement itself was a 12-month stint within the formulation development team at the company’s site in Hoddesdon (I still wouldn’t be able to point this out to you on a map!). During the year, I was exposed to and involved in much more than I expected. If, like me, you expected a year of photocopying and running errands, then think again.

I couldn’t believe how soon I was thrown in the deep end! The CDMO work environment is very dynamic, any minute a client can email in a request to change or add to a contract and then its all hands on deck to get the work done. After only a few weeks of training (and reading lots of documentation), I was straight into helping my supervisor with the production of a batch of tablets for stability testing. And that was only the start.

Some examples of things I did while on placement include: qualification of fridges, freezers and digital clocks (yes, even clocks have to qualified in a GMP environment), production of stability batches (many, many tablets and capsules), installation and set up of new automatic balances (terrifyingly expensive pieces of kit) and completing a case study for the team.

The case study

Case studies are carried out on topics the team have little experience in or to show off their expertise to potential clients.

A case study I was asked to complete while on placement looked at tablet coatings. Specifically, the team wanted to learn more about (and show clients we knew about) titanium dioxide free coatings and how they compared to regular, titanium dioxide containing coatings. I won’t bore you with the legislative details, but to make a long story short, the EU may ban this compound from tablet coatings. This would be a bad thing as it would mean many drug shortages and discontinuations, as it has many very useful properties. Other compounds with similar properties simply do not exist.

I was given free reign on how to complete the case study, which gave me a real sense of pride as the team felt confident enough in my abilities to complete this important piece of work for them. Completing the case study also gave me an excellent piece of work to write my Placement Report on.

Another opportunity which arose from completing this case study was submitting a poster and abstract to the APS (Academy of Pharmaceutical Sciences) to present at their annual PharmSci conference.

APS and PharmSci

After completing my case study and placement report, and as my placement was coming to an end, my supervisor suggested submitting an abstract and poster of my work to the APS for their PharmSci annual conference.

I thought this was an amazing opportunity which I couldn’t pass up on, so in the last few days of my placement I worked hard to prepare both a poster and abstract detailing the work we had completed on the case study.

To my surprise, both were accepted for presentation at the conference, and the abstract was also selected for an oral presentation (at the time this terrified me, but I soon realised it was an amazing opportunity)!


Attending the (all expenses paid!) conference was truly the highlight of my year, and being able to present the work I had spent many months on was an extremely proud moment.

Presenting at the APS PharmSci conference

I can’t recommend doing a placement enough, irrespective of if it involves lab work, office work or a combination of the two, it really is a fantastic and formative experience. Not only do you get paid (usually quite well!) for a year, but you also learn and are exposed to so many new things which could eventually be what you decide to do when you leave university.

If you are in two minds over doing a placement or not, take this as a sign to go for it!

You won’t regret it!

A year in NHS labs

By Chloe Heppenstall

What goes on in the NHS laboratories? 

Rather than a research-based placement, my time in the NHS laboratories involved completing routine assays to test samples and deliver crucial patient results as soon as possible. I was part of the Immunology team within Laboratory Medicine, however there are numerous different departments, such as haematology, virology, microbiology, or chemistry. Having previously worked in the NHS as a domestic, I thought I knew a lot about what happens in the hospitals, but this placement was a huge eye opener as to how much goes on behind the scenes! 

Thank you NHS by Karolina Grabowska from Pexels

Why I applied for a placement year. 

As I was heading into my second year of University, I was developing a deep interest for Immunology, however I was unsure on what careers would involve this work, and if I would enjoy it. I figured a laboratory-based placement would be the best way for me to understand what work in this sector looks like, and if it was something that I could thrive in. From enjoying my time in the labs at university, I knew a hands on, lab-based placement would be something for me. By taking on this exciting opportunity in the Immunology laboratory in the NHS, I was able to utilise my skill set and knowledge further in an area I was keen on progressing into. 

Me wearing different PPE

What does a typical day look like? 

Each day differed depending on which bench I was allocated to. Within the department, there are 7 different benches, which a Biomedical Scientist would usually spend between 2-6 months on before rotating. These benches involve techniques such as gel electrophoresis, immunofluorescence, immunofixation, immunodisplacement, and automated and manual assays. As part of my placement, I had the opportunity to rotate around all the benches, and each bench was dissimilar to the last. Depending on turnaround times, any backlogs of samples, or any additional work the lab was taking on from other labs, one bench could be a lot busier compared to other benches, and require more staff members to help.  

Identifying monoclones via gel electrophoresis] 

What did I learn? 

In addition to utilising laboratory techniques I acquired during university, I learnt a range of new methods which I will carry as valuable experience for future job prospects. Furthermore, I learnt the importance of turnaround times, and the impact which can occur for the patient if these are not met. My professionalism also grew, as I frequently had to speak to other healthcare professionals, such as nurses in A&E, or midwives. Outside of the lab, the clinical scientists held lectures and journal club sessions, which focussed on the clinical applications and impact of the assays we were completing in the laboratory. This was useful as time in the lab can become very fast paced and repetitive, and it can be easy to forget why you are doing what you are doing. Finally, I made a lot of friends who share similar interests and hobbies to myself, which enabled me to develop a healthy work-life balance. 

Me extracting calprotectin samples in a fume cupboard

What did I find challenging? 

Although many people warned me, adjusting to the 9-5 working life was extremely difficult. Despite my day finishing at 5 and having my weekends off, I have been just as tired working 9-5 than I was at university with loads of deadlines! On the other hand, there was no stress like there is with university, and if I ever had any problems with work, or I did not understand a concept, the team in Immunology were so welcoming and would give me as much time as I needed to understand and complete something. 

Would I recommend a placement to other students? 

Absolutely. The skills and experience you acquire whilst on a placement are invaluable, and put you in the best position for applying to jobs after university. If you are seeking hands on experience and a taste of the real world outside of university, do not hesitate to apply to placement opportunities! Aside from the unique skillset I have acquired, I have also been given opportunities to meet new people and discuss their opinions on interesting real-life assay topics, and my potential career in the NHS. I feel confident in a laboratory workplace, which is something I never thought I would be saying! 

I now cannot wait to complete my final year at university, obtain my degree, and take my skillset further either in postgraduate studies or in a job. 

Would your blood glow?

By Sarah Holder

The Beginning 

All the way back at the start of my second year at Newcastle University, the thought of a placement year was a nice one, but I never thought I’d be one of the lucky few to be offered one! When I came across the advert for the job at Labcorp Huntingdon, I knew it would be the only intern position I wanted to apply for. The role sounded perfect and it was located only half an hour from my home village. I sent off my initial application and then received an invite for an interview! And then another! And another! I couldn’t believe it when I received a phone call in January to say I had been offered the intern position for Immunology and Immunotoxicology 2022-2023. Brilliant! 

Background to my Project 

Human blood is made up of several major components including plasma, platelets, red blood cells and white blood cells. White blood cells are involved in the body’s response to infection and need to be tested separately to the rest of the blood components to see the best results.  

Via Giphy.

Infections can come in the form of viruses or bacteria. Viruses present markers called epitopes on their surface which the white blood cells use to identify what they are. Bacteria don’t directly present these epitopes but via white blood cells they infect which present their epitopes for them. When these epitopes are come across in the bloodstream, specific white blood cells release chemicals called cytokines to activate the immune response and fight the infection. We were adding epitopes artificially in the form of our stimulants to elicit a response from six different human donors and judge the stimulant that gives the clearest response across the six blood samples.   

My Project 

My project during my time on placement at Labcorp had two parts. Improving the white blood cell isolation method and investigating white blood cell responses to positive controls we added to them and attaching fluorescent green and red markers to the different cytokines produced. We had longer to plan my project than expected so it didn’t get into the lab until May, creating more pressure for everything to go smoothly once it was underway. If anything had gone drastically wrong, we wouldn’t have had enough time to order the reagents required for another attempt. The images taken at the end were full of fluorescent spots so the project worked! 

Via Giphy

My project has provided a future method for FluoroSpot assays to be carried out at Labcorp on our Huntingdon site which will hopefully be able to bring more revenue into I&I. Future research into the method we developed for my project could be done to optimise it further and make it a more streamlined process. 

Life on Placement 

I was lucky enough to not only secure a placement but secure a placement I could commute to from my home. Thankfully, my parents were happy to have me back for another year! While the 6:45am wakeup call wasn’t my favourite, I could spend my evenings visiting my friends from home, which was lovely. I worked a mixture of 8am-4pm and 8:30am-4:30pm throughout the week and it was nice actually being able to catch a glimpse of daylight in the winter when leaving at 4pm instead of both arriving and leaving in what feels like the dead of night every day. 

Every month a department social was held by the I&I Social Committee. My favourites were the Halloween bar crawl, Christmas party and lab getaway weekend to a lakeside cabin with the team.  These really helped me to feel part of the team during my time working at Labcorp. 

Via Giphy

Summary 

I would really recommend a placement year to anyone considering one, the lab experience gained is a perfect CV addition for life after university and the additional skills of working in a team and independently while in an industry setting are invaluable. I was very fortunate and had the best line manager in terms of supporting my transition into a working environment, this was aided massively by the chocolate that magically appeared on my desk every Friday. I’m not sure what my future after university is going to be yet, but thanks to my placement year I know I can join a workplace and adapt to fit in very quickly, and training can be provided if I feel I have any gaps in my knowledge for my future role. No question is a stupid question! 

Day in the life of a student dietitian on placement

By Anna Slater

I’m Anna, a stage 2 Dietetics student and a social media intern for the Biomedical, Nutritional and Sports Science school. Before Christmas we took part on a few placement experiences at care settings and also Simply Food Solutions, a company that specialises in making texture modified foods. As part our degree, we must partake in 1000 hours of voluntary placement to help teach us important skills and expertise to help us become better dietitians. During these two days I learnt values that are important to use when working as a dietitian, particularly with those who have dementia.  

The care setting I was placed at is called St Anthony’s of Padua community centre for a day, which is a charitable organisation providing a wide range of care and support services enhancing the social and physical wellbeing of adults with mild-complex care needs such as dementia or impaired mobility. In the morning I was placed in the Day Service, where the service users come from 9-3pm for Breakfast and Lunch and to socialise with the other service users. We spoke to the chef in the Day Service kitchen and she discussed all the conditions she had to cater for. They had different rimmed plates – green and yellow. The green plates were for service users who had dementia, because it makes it easier for them to see the food on their plate. The yellow plates were for those who had to have levelled diets based on the IDDSI framework (International Dysphagia Diet Standardisation Initiative). The IDDSI framework describes a levelled system of food and was created for patients who have been diagnosed with dysphagia, which means they have swallowing difficulties.

IDDSI levelled system – photo from IDDSI – IDDSI Framework

The highest levelled diet they had to cater for was for a level 4, the consistency of which being pureed so they don’t require any chewing and promotes safe swallowing for the service user.  The chef would purify the foods herself using a blender and would make sure that he had lots of food options that the service user could enjoy whilst maintaining a safe swallow. One of the service users was a type 1 diabetic who was injecting insulin, so they had to make sure that they had sugar-free options for dessert. I felt like this was a valuable experience because I really learnt how to communicate with empathy and how to approach conversations with people who have difficulty conversing. It was clear the positive impact that St Anthony’s had on the quality of life of the service users, and keeps them being able to socialise. 

After lunch, I joined one of the staff members on their home visits. We went to a few houses with service users who had chronic conditions such as type 2 diabetes or who had had falls. The purpose of the carers was to assist the service users to check in on them and make sure they are eating, taking their medication, and also to help with any basic needs such as showering or washing. My role here was to ask the service user questions about their diet and how they manage their condition.  

We then had a morning placed at the Simply Food Solutions factory in South Shields. Simply Food Solutions is a company that create texture-modified foods for patients with dysphagia. Dysphagia is a condition where the patients has difficulty swallowing. The main consumers are hospitals where they provide these products so the patients have a more enjoyable eating experience. The company’s primary objective is to produce food that meets home-cooked standards, making sure they are authentic and tasty. Each dish complies with the IDDSI guidelines for texture. We were given a tour of the factory, and we were required to wear protective gear including hair nets, shoe covers and special white coats, to comply with strict food hygiene regulations. You can see the outfit in its full glory in the picture below, and all layered up prepared for the cold freezer rooms! 

Getting dressed up in our protective gear to explore the factory (with lots of cosy layers underneath ready for the freezer room!)

The first part of the factory was a huge cold storage freezer, which was a whole room! Separate freezer rooms were designated for meat, vegetables and dairy. It was so cold when we went in them, so it was a good job that we had layered up! We were then showed where the meals were prepared and cooked, and there were huge ‘kettles’ which held around 300 litres of water. The meals were cooked in these kettles, and then underwent a rapid cooling process in a blast chiller. Following this, they were transferred to large blenders equipped with blades designed to ensure that the food met the specified texture. Post-blending, the food was sent to packaging where individual workers carefully weighed each portion before automated machines sealed the packages. The final step involved placing the packaged items into blast freezers, preparing them for shipment to consumers. After the factory tour we were able to test the meals to make sure they met the necessary requirements by using certain utensils and seeing how the food behaved. We were given checklists that matched the IDDSI framework, and using forks and our fingers we had to assess the texture, appearance and thickness of the foods. We then tried to recreate these back in the food labs at university inspired by the foods we saw at Simply Foods Solutions.

Our recreations of the texture modified foods we saw at Simply Food Solutions made in the food labs

Overall, I thoroughly enjoyed these placement sessions, and I learned a lot about the importance of texture modified diets and how they can improve the quality of life with people with dysphagia. Despite the texture being different, the taste and appearance of food still has a huge impact on the enjoyment of eating. The more appetising the food looks, the more likely it is that the patient is going to eat it, which is very important to maintain a healthy weight and to avoid malnutrition, which is common with dysphagia. The texture is also important to prevent choking hazards. For me it also highlighted the importance of care settings like St Anthony’s providing places where older and isolated people can come together and socialise, which greatly improves their quality of life and morale. The most valuable skill I gained was the ability to communicate with all the service users and approach conversations despite certain barriers. These were two very enjoyable sessions and I am looking forward to my 1-week NHS placement in Easter, where I will be based in St Nicholas’ Hospital in Gosforth, where I will get a greater insight into what a Dietitian’s role within the hospital entails.  

For more information on Dietetics and how to apply, visit Dietetics MDiet | Undergraduate | Newcastle University (ncl.ac.uk) 

Links: 

Overview – St Anthony of Padua Care Services – NHS (www.nhs.uk) 

IDDSI – IDDSI – IDDSI Framework

Home – Simply Food Solutions 

A Placement Year at GSK – Sequencing Genomes

By: Natalie Taylor – BSc Biomedical Sciences

Edited by: Laila Hussain

Second year of uni rolled around, and I realised I hardly had any lab experience (thanks COVID). This was a dilemma I attempted to remedy by applying for a placement year. I never considered I’d be accepted by such a prestigious company as GSK. Even less did I consider I would be working in a field as interesting as genetics. The application stress paid off! I was placed in the Discovery Genomics department working on single cell RNA sequencing. This basically means reading genes that are currently ‘switched on’ (expressed). Knowing this information is crucial for understanding disease, as we can quantify which genes were switched on/off in disease states compared to healthy states. With this information we can then get an idea of the genes function and thus, what therapeutic action to take. 

My Application Journey – It’s ok not to know everything!

When I say I was almost 100% sure I failed my interview I was not joking. GSK’s interview stage was split into two sections. One half was situational questions such as “tell us a time you faced a challenge” etc. The other was technical questions. This was where I flopped. I didn’t know the answer to any of the questions! However, I discovered the point of these questions was not only to test your scientific knowledge, this can be taught, but to also see how you manage uncertainty and to test your resilience. It was a daunting experience, but thanks to the kind interviewers and some persistence I managed to give all the answers a go. This was what the interviewers were looking for!

Two days later I received a call from one of the interviewers offering me the placement!

My-day-to-day 

As I mentioned above, I’m working on sequencing (or reading) the genes of individual cells. This means I’m in the lab a lot! I get to work on many different diseases and cell types, which all involve working with very small volumes. Attention to detail is paramount – something I’ve had to learn the hard way! 

A visual example of the types of tubes and volumes we typically work with in RNA sequencing- sometimes even smaller! Image from: unsplash

I also get to use lots of very cool – and very expensive – machines. The machine pictured below on the left is what sequences RNA and the one to the right is a robot that can do a big portion of the lab work involved with preparing the RNA for sequencing for you. It has some limitations though, so I mostly performed my experiments manually by hand. 

Illumina Sequencer (Left) & Chromium Connect (Right): Photos from 10x Genomics and Illumina

After about three months of training, I started planning and carrying out my own experiments independently. I got the chance to sequence many different immune cells, including T cells and macrophages as part of active experiments in the search for potential cancer therapeutics. Apart from single cell RNA sequencing, I’ve also been fortunate to perform a CRISPR knock out experiment on B cells whilst using cutting-edge automation platforms such as the Dragonfly and Bravo.  

On a typical day, my experiments take around 6 hours to reach a safe stopping point. Luckily, I’m able to get a few breaks in when my samples are incubating. During these breaks, I take full advantage of all of the green space at GSK Stevenage. It’s quite normal for employees to go on regular walks around the site – breaks are very encouraged which is nice!

GSK Campus and Labs in Stevenage: Photos from GSK’s Website

Outside of lab work, I’ve also gotten involved with the wider community at GSK by being a part of a committee for students called IP Unite and an employee resource group called Women’s Leadership Initiative (WLI). My role in these groups varies, typically I will plan and host events aimed to foster new relationships and grow networks. One of the scariest events I held was a PhD information event with IP Unite that involved me speaking in front of 100 people in a lecture theatre – luckily I was only introducing speakers and closing the event – still, it was very outside of my comfort zone! In general, I find that the placement pushes me outside of my comfort zone, but that’s what yields the most growth so I know it’s super beneficial. 

Overall, the placement has been the best experience, better than I expected! I have grown so much as a scientist and a person. I feel much more prepared for life after uni. For now though, I’m just ready to tackle final year!

My Experience as a Year In Industry Student

By Joel Tyler, BSc Physiological Sciences

Edited by Maddie Wildridge

Reckitt is a Fast Moving Consumer Goods (FMCG) company with offices and employees spread out across the world. Founded in 1870, Reckitt started off by selling laundry starch in Hull, now, Reckitt operates in a range of markets and is the owner of various health and medicinal brands such as; Neurofen, Strepsils, Dettol, Vanish and Durex to name a few.

Examples of some Reckitt products sold around the world

My placement year was a lab-based role involved in working for the brand Veet, this included both formulation manufacturing and analytical testing for the depilatory cream products currently available to buy in shops as well as a new product being developed and to be released in the near future.

A Day in the Life

Using a Light Microscope to examine the structure of a hair sample

Due to the fast paced environment (as an FMCG company), I found that there was always something to do all the time and the days/weeks were fairly similar. This is because of the constant manufacturing of different formulations of new products to be tested under different stability conditions, and then followed by analytical testing of the formulations to identify which was the best product.

Therefore, my normal day would start with a team meeting to discuss where everyone was at with formulation/testing work and to discuss steps/processes going forward or if anything had failed/gone wrong with the batch. After, I would go to the lab to complete any formulation/analytical testing which needed to be done.

I enjoyed this working routine as it meant I gained far more lab experienced than I initially thought I would, it was always very clear what work I needed to be doing and I was always given lots of support if things ever went wrong. I would say I definitely wasn’t treated as a ‘student’ but a very integral part of the team which also surprised me!

Student Project
In the second half of my placement, I organised and created a project alongside my line manager which involved testing the tensile strength of hair using a texture analyser and a brand new test method. I also presented my results to the rest of the Veet brand to explain my findings.

Hair sample being tested in the Texture Analyser to investigate the tensile strength

During my project I had to test thousands of individual hair samples and as a result became the most experienced within the lab at using the texture analyser, this meant that I had the opportunity to present and perform samples to higher up executives within the company (and even the Global Head of R&D) which was an amazing experience.

A Becomix machine used to formulate and manufacture different depilatory creams during my placement year

Why I Chose To Do a Placement
I decided during first year of my degree that I wanted to do a placement, specifically a lab based placement, because I was enjoying being in the lab at university but I was curious if I would enjoy working in a lab as a full time job to give myself an idea for post graduate jobs.

Having completed my full year, I now know I could happily work in a lab after university, so applying for lab based roles isn’t a big risk but also that I know I can work efficiently and thrive under the environment. My placement gave me many challenges along the way (which is natural when learning new things in a short space of time) but I gained valuable and employable experience in overcoming these obstacles and realised that I feel confident within a lab setting.

I Would Highly Recommend a Placement!
Completing my placement year was definitely one of the most important things I have done within my life. The obvious reasons being all the different skills and attributes which I learnt/developed along the way, but also, the experiences which are available in just one year really surprised me, with the huge amounts of social networking needed to be done for my day to day job, I found myself naturally speaking to and shadowing other departments, creating professional relationships which will last for life. So I would say even if you are even considering to apply for placements, just go for it because you won’t regret it!