In the ‘Overview‘ section of this site the handout (linked to the TSM introductory lecture for the ‘Tired all the time’ case) discusses the difficulty of making psychiatric diagnoses. The lecture and handout refer to ICD-10 and DSM-IV but both are being reviewed with the next iterations of both classification systems due out soon. There is an interesting article in Wired magazine that includes an interview with Allen Frances who was lead editor of DSM-IV where he talks of his concerns over DSM-V.
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